Results 51 to 60 of about 889 (135)

Knockout of the Intracellular Calcium Conducting Ion Channel Mitsugumin 23 (MG23) Protects Against Pressure Overload Induced Left Ventricular Hypertrophy and Cardiac Dysfunction

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
In an angiotensin‐II‐induced pressure overload induced heart failure mouse model, expression of MG23 is increased. Knockout of Mg23 protected hearts against Angiotensin‐II ‐induced cardiac hypertrophy. Mg23‐KO mice also displayed a marked decrease in left ventricular fibrosis and had normal cardiac functioning compared to wild type animals.
Amy M. Dorward   +10 more
wiley   +1 more source

Outlook: Spring 2004 [PDF]

open access: yes, 2004
Alumni publication of the Boston University School of Dental ...
Office of External Affairs, Boston University Goldman School of Dental Medicine
core   +1 more source

Role of quorum sensing in UVA-induced biofilm formation in Pseudomonas aeruginosa [PDF]

open access: yes, 2020
Pseudomonas aeruginosa, a versatile bacterium present in terrestrial and aquatic environments and a relevant opportunistic human pathogen, is largely known for the production of robust biofilms.
Costa, Cristina Susana   +2 more
core   +1 more source

Four novel taxa of cyanobacteria from a unique thermal cave habitat in Vromoner Canyon, Albania

open access: yesJournal of Phycology, Volume 61, Issue 5, Page 1394-1422, October 2025.
Abstract Thermal and cave habitats on nearly all continents have been a substantial source of new cyanobacterial genotypes and morphotypes that expanded with the dawn of the era of molecular phylogenetics. In this study, we investigated the cyanobacterial flora of an extreme habitat of recently discovered caves with sulfur‐rich thermal springs, using ...
Jan Pokorný   +3 more
wiley   +1 more source

Aggregatibacter (Actinobacillus) actimycetemcomitans leukotoxin and human periodontitis – A historic review with emphasis on JP2

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 34, Issue 4, Page 186-193, April 2018., 2018
Abstract Aggregatibacter (Actinobacillus) actimycetemcomitans (Aa) is a gram‐negative bacterium that colonizes the human oral cavity and is causative agent for localized aggressive (juvenile) periodontitis (AgP). In the middle of 1990s, a specific JP2 clone of belonging to the cluster of serotype b strains of Aa with highly leukotoxicity (leukotoxin ...
Chi‐Cheng Tsai   +5 more
wiley   +1 more source

Convergent evolution of cytochrome P450s underlies independent origins of keto-carotenoid pigmentation in animals [PDF]

open access: yes, 2019
Keto-carotenoids contribute to many important traits in animals, including vision and coloration. In a great number of animal species, keto-carotenoids are endogenously produced from carotenoids by carotenoid ketolases.
Bryon, Astrid   +9 more
core   +1 more source

Rheumatoid Arthritis-Associated Autoimmunity Due to Aggregatibacter actinomycetemcomitans and Its Resolution With Antibiotic Therapy [PDF]

open access: yes, 2018
Background:Aggregatibacter actinomycetemcomitans (Aa) is a Gram-negative coccobacillus recognized as a pathogen in periodontitis and infective endocarditis. By producing a toxin (leukotoxin A, LtxA) that triggers global hypercitrullination in neutrophils,
Amarshi Mukherjee   +8 more
core   +1 more source

New frontiers on adjuvants drug strategies and treatments in periodontitis [PDF]

open access: yes, 2021
Causes of the progression of periodontitis such as an imbalance between the immune response by the host by the release of inflammatory mediators in the response of the oral pathogenic dysbiotic biofilm have been identified.
Dalessandri D.   +5 more
core   +1 more source

Comparative genomic hybridization and transcriptome analysis with a pan‐genome microarray reveal distinctions between JP2 and non‐JP2 genotypes of Aggregatibacter actinomycetemcomitans

open access: yesMolecular Oral Microbiology, 2012
SummaryIt was postulated that the highly virulent JP2 genotype of Aggregatibacter actinomycetemcomitans may possess a constellation of distinct virulence determinants not found in non‐JP2 genotypes. This study compared the genome content and the transcriptome of the serotype b JP2 genotype and the closely related serotype b non‐JP2 genotype of A ...
Y, Huang   +5 more
openaire   +2 more sources

Periodontal pathogens and cancer development

open access: yesPeriodontology 2000, Volume 96, Issue 1, Page 112-149, October 2024.
Abstract Increasing evidence suggests a significant association between periodontal disease and the occurrence of various cancers. The carcinogenic potential of several periodontal pathogens has been substantiated in vitro and in vivo. This review provides a comprehensive overview of the diverse mechanisms employed by different periodontal pathogens in
Yuxi Zhou, Joerg Meyle, Sabine Groeger
wiley   +1 more source

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