Diversity and evolution of leukotoxin operons in Staphylococcus aureus [PDF]
mSystemsStaphylococcus aureus is a globally significant and opportunistic pathogen equipped with a diverse arsenal of virulence factors, including bi-component leukotoxins that play a central role in immune evasion and tissue damage. Despite extensive functional
Stephanie S. R. Souza +2 more
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Toxins, 2018 Bibersteinia trehalosi and Mannheimia haemolytica, originally classified as Pasteurella haemolytica biotype T and biotype A, respectively, under Genus Pasteurella has now been placed under two different Genera, Bibersteinia and Mannheimia, based on DNA ...
Subramaniam Srikumaran +2 more
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Chrysin and Luteolin from Moroccan Propolis to Prevent Aggressive Periodontitis Caused by Aggregatibacter actinomycetemcomitans Leukotoxin: A Computer-Aided Drug Design Approach [PDF]
PharmaceuticalsBackground: Aggregatibacter actinomycetemcomitans is a Gram-negative, facultative anaerobic, immobile oral bacterium responsible for the secretion of virulence factors, namely leukotoxin (LtxA), a large exotoxin of the RTX family that enables the ...
Doha EL Meskini +6 more
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Toxins, 2011 Aggregatibacter actinomycetemcomitans has been described as a member of the indigenous oral microbiota of humans, and is involved in the pathology of periodontitis and various non-oral infections. This bacterium selectively kills human leukocytes through
Anders Johansson
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Immunogenicity and protective efficacy of seven candidate vaccines boosted with recombinant proteins, whole-cell bacterins of three serotypes of Mannheimia haemolytica, and an emulsion-type adjuvant [PDF]
Frontiers in Veterinary ScienceIntroductionMannheimia haemolytica is a primary cause of bovine respiratory disease, leading to substantial economic losses in the livestock industry.
Aslı Balevi +4 more
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The Iraqi Journal of Veterinary Medicine, 2012 This study was conducted to extract and titrate the leukotoxin of Fusobacterium necrophorum isolates recovered from 75abscesses found in 24 livers of slaughtered cattle in Sulaimaniyah region.
Suha Ali Hussein
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Biological and molecular characterization of a sheep pathogen isolate of Mannheimia haemolytica and leukotoxin production kinetics [PDF]
Veterinary World, 2021 Background and Aim: Mannheimia haemolytica (Mha) is a common agent of pneumonia in ruminants globally, causing economic losses by morbidity, mortality, and treatment costs.
Dounia Bkiri +10 more
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Leukotoxic activity of Aggregatibacter actinomycetemcomitans and periodontal attachment loss. [PDF]
PLoS ONE, 2014 Aggregatibacter actinomycetemcomitans is a Gram-negative periodontitis-associated bacterium that expresses a toxin that selectively affects leukocytes.
Carola Höglund Åberg +4 more
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Plasma Linoleate Diols Are Potential Biomarkers for Severe COVID-19 Infections
Frontiers in Physiology, 2021 Polyunsaturated fatty acids are metabolized into regulatory lipids important for initiating inflammatory responses in the event of disease or injury and for signaling the resolution of inflammation and return to homeostasis. The epoxides of linoleic acid
Cindy B. McReynolds +13 more
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β-Hemolysis May Not Be a Reliable Indicator of Leukotoxicity of Mannheimia haemolytica Isolates
Toxins, 2018 Mannheimia (Pasteurella) haemolytica causes bronchopneumonia in domestic and wild ruminants. Leukotoxin is the critical virulence factor of M. haemolytica. Since β-hemolysis is caused by a large number of leukotoxin-positive M. haemolytica isolates,
Jegarubee Bavananthasivam +5 more
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