Results 31 to 40 of about 3,520 (213)
Monoclonal antibodies to leukotoxin of Actinobacillus actinomycetemcomitans [PDF]
Infection and Immunity, 1985 Hybridoma cell lines which produce monoclonal antibodies to a leukotoxin from Actinobacillus actinomycetemcomitans were prepared. The monoclonal antibodies were selected for their ability to neutralize the cytotoxic activity of the leukotoxin and recognize the toxin on nitrocellulose blots. The antibodies belonged to either the immunoglobulin G1 (IgG1)
J M, DiRienzo +4 more
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Immunosuppressive properties of Actinobacillus actinomycetemcomitans leukotoxin [PDF]
Infection and Immunity, 1988 Actinobacillus actinomycetemcomitans produces a leukotoxin that kills human polymorphonuclear cells (PMNs) and monocytes but not lymphocytes. In this study, we examined A. actinomycetemcomitans leukotoxin for its ability to alter human peripheral blood lymphocyte (HPBL) responsiveness.
G, Rabie, E T, Lally, B J, Shenker
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Frontiers in Veterinary Science, 2021 We evaluated the efficacy of three vaccine formulations containing different combinations of proteins (43K OMP, leukotoxin recombinant protein PL4 and hemolysin recombinant protein H2) and killed whole cell Fusobacterium necrophorum in preventing liver ...
Jiawei Xiao +7 more
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Aggregatibacter Actinomycetemcomitans – A Tooth Killer? [PDF]
Journal of Clinical and Diagnostic Research, 2014 Strong evidence is available on Aggregatibacter actinomycetemcomitans (A.a) on its role as the causative agent of localised juvenile periodontitis (LJP), a disease characterised by rapid destruction of the tooth-supporting tissues.
Manoj Raja, Fajar Ummer, C.P Dhivakar
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Identification and characterization of the Pasteurella haemolytica leukotoxin [PDF]
Infection and Immunity, 1987 The identification and chromatographic characterization of the leukotoxin of Pasteurella haemolytica is described. The toxin, which has an apparent native molecular weight of greater than 400,000 as judged by gel exclusion chromatography, has a 105-kilodalton (105K) polypeptide as its major protein component.
Y F, Chang +3 more
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Journal of Oral Microbiology, 2015 The expression of the leukotoxin of Aggregatibacter actinomycetemcomitans is regulated by the leukotoxin promoter. A 530-bp deletion or an 886-bp insertion sequence (IS) element in this region has earlier been described in highly leukotoxic isolates ...
Rolf Claesson +4 more
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Comparative protection of small ruminants against Mannheimia haemolytica infection by inactivated bacterin and toxoid vaccines [PDF]
Veterinary World, 2023 Background and Aim: Mannheimia haemolytica causes respiratory infection and mortality in sheep and goats, similar to the effects in cattle, which causes major economic damage.
Dounia Bkiri +4 more
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Secretion of the Pasteurella leukotoxin by Escherichia coli [PDF]
FEMS Microbiology Letters, 1989 Nucleic acid sequence analysis has indicated that the leukotoxin determinant from Pasteurella haemolytica is related to the hemolysin determinant from E. coli. The cloning and expression in E. coli of the lktCA genes has been previously reported, but the existence of leukotoxin secretory genes equivalent to hlyBD has not been documented. In this report
Y F, Chang +3 more
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Screen for Leukotoxin Mutants in Aggregatibacter actinomycetemcomitans : Genes of the Phosphotransferase System Are Required for Leukotoxin Biosynthesis [PDF]
Infection and Immunity, 2008 ABSTRACT Aggregatibacter (formerly Actinobacillus ) actinomycetemcomitans is a pathogen that causes localized aggressive periodontitis and extraoral infections including infective endocarditis. Recently, we reported that A.
Maria P, Isaza +3 more
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Journal of Indian Society of Periodontology, 2018 Context: Aggregatibacter actinomycetemcomitans (A.a) serotypes may add some important information of the pathogenetic background of periodontal infections. A.a leukotoxin is an important virulence factor in the pathogenesis of periodontal disease and its
Sudhakar Shuntikudege Suprith +3 more
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