Results 31 to 40 of about 2,921 (175)

Aggregatibacter Actinomycetemcomitans – A Tooth Killer? [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Strong evidence is available on Aggregatibacter actinomycetemcomitans (A.a) on its role as the causative agent of localised juvenile periodontitis (LJP), a disease characterised by rapid destruction of the tooth-supporting tissues.
Manoj Raja, Fajar Ummer, C.P Dhivakar
doaj   +1 more source

Detection of a 640-bp deletion in the Aggregatibacter actinomycetemcomitans leukotoxin promoter region in isolates from an adolescent of Ethiopian origin

open access: yesJournal of Oral Microbiology, 2015
The expression of the leukotoxin of Aggregatibacter actinomycetemcomitans is regulated by the leukotoxin promoter. A 530-bp deletion or an 886-bp insertion sequence (IS) element in this region has earlier been described in highly leukotoxic isolates ...
Rolf Claesson   +4 more
doaj   +1 more source

Comparative protection of small ruminants against Mannheimia haemolytica infection by inactivated bacterin and toxoid vaccines [PDF]

open access: yesVeterinary World, 2023
Background and Aim: Mannheimia haemolytica causes respiratory infection and mortality in sheep and goats, similar to the effects in cattle, which causes major economic damage.
Dounia Bkiri   +4 more
doaj   +1 more source

Increased leukotoxin production: Characterization of 100 base pairs within the 530 base pair leukotoxin promoter region of Aggregatibacter actinomycetemcomitans

open access: yesScientific Reports, 2017
Aggregatibacter actinomycetemcomitans leukotoxin (LtxA) is a major virulence factor that kills leukocytes permitting it’s escape from host immune surveillance. A. actinomycetemcomitans strains can produce high or low levels of toxin.
Vandana Sampathkumar   +3 more
doaj   +1 more source

Serotypes of Aggregatibacter actinomycetemcomitans in relation to periodontal status and assessment of leukotoxin in periodontal disease: A clinico-microbiological study

open access: yesJournal of Indian Society of Periodontology, 2018
Context: Aggregatibacter actinomycetemcomitans (A.a) serotypes may add some important information of the pathogenetic background of periodontal infections. A.a leukotoxin is an important virulence factor in the pathogenesis of periodontal disease and its
Sudhakar Shuntikudege Suprith   +3 more
doaj   +1 more source

The role of Aggregatibacter actinomycetemcomitans and its leukotoxin in periodontitis

open access: yesJournal of Oral Microbiology, 2017
Aggregatibacter actinomycetemcomitans is a Gram-negative periodontitis-associated bacterium that expresses a toxin that selectively affects leukocytes. Leukotoxin is encoded by an operon belonging to the core genome of this bacterial species.
Anders Johansson   +4 more
doaj   +1 more source

Interactions of extracts from selected chewing stick sources with Aggregatibacter actinomycetemcomitans

open access: yesBMC Research Notes, 2012
Background Aggregatibacter actinomycetemcomitans produces a leukotoxin that activates a pro-inflammatory death of human monocytes/macrophages. A specific clone of this bacterium (JP2) has a 530-base pair deletion in the leukotoxin promoter gene and ...
Kwamin Francis   +3 more
doaj   +1 more source

Molecular and phylogenetic study of Staphylococcus aureus isolated from human and cattle of Al-Qadisiyah Governorate, Iraq [PDF]

open access: yesVeterinary World, 2019
Aim: This study was designed to detect the prevalence of Staphylococcus aureus, to estimate the frequency of methicillin resistance gene (mecA), femA (specific gene for S.
Ahmed Jasim Neamah   +4 more
doaj   +1 more source

Leukotoxin and pyrogenic toxin Superantigen gene backgrounds in bloodstream and wound Staphylococcus aureus isolates from eastern region of China

open access: yesBMC Infectious Diseases, 2018
Background The bicomponent leukotoxins and the pyrogenic toxin superantigens (PTSAgs) are important virulence factors of Staphylococcus aureus. It is necessary to survey the prevalence and expression of these toxin-encoding genes for understanding the ...
Chunyan He   +8 more
doaj   +1 more source

Aggregatibacter Actinomycetemcomitans: Clinical Significance of a Pathobiont Subjected to Ample Changes in Classification and Nomenclature

open access: yesPathogens, 2019
Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium that is part of the oral microbiota. The aggregative nature of this pathogen or pathobiont is crucial to its involvement in human disease.
Niels Nørskov-Lauritsen   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy