Results 11 to 20 of about 2,921 (175)
Therapeutic Applications of Aggregatibacter actinomycetemcomitans Leukotoxin [PDF]
PathogensAggregatibacter actinomycetemcomitans is a Gram-negative oral bacterium that has been primarily studied for its role in causing periodontal disease. The bacterium has also been implicated in several systemic diseases such as endocarditis and soft tissue ...
Scott C. Kachlany, Brian A. Vega
doaj +4 more sources
Diversity and evolution of leukotoxin operons in Staphylococcus aureus [PDF]
mSystemsStaphylococcus aureus is a globally significant and opportunistic pathogen equipped with a diverse arsenal of virulence factors, including bi-component leukotoxins that play a central role in immune evasion and tissue damage. Despite extensive functional
Stephanie S. R. Souza +2 more
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Chrysin and Luteolin from Moroccan Propolis to Prevent Aggressive Periodontitis Caused by Aggregatibacter actinomycetemcomitans Leukotoxin: A Computer-Aided Drug Design Approach [PDF]
PharmaceuticalsBackground: Aggregatibacter actinomycetemcomitans is a Gram-negative, facultative anaerobic, immobile oral bacterium responsible for the secretion of virulence factors, namely leukotoxin (LtxA), a large exotoxin of the RTX family that enables the ...
Doha EL Meskini +6 more
doaj +2 more sources
Toxins, 2018 Bibersteinia trehalosi and Mannheimia haemolytica, originally classified as Pasteurella haemolytica biotype T and biotype A, respectively, under Genus Pasteurella has now been placed under two different Genera, Bibersteinia and Mannheimia, based on DNA ...
Subramaniam Srikumaran +2 more
exaly +3 more sources
Evolution of the leukotoxin promoter in genus
BMC Evolutionary Biology, 2009 Background The Mannheimia species encompass a wide variety of bacterial lifestyles, including opportunistic pathogens and commensals of the ruminant respiratory tract, commensals of the ovine rumen, and pathogens of the ruminant integument.
Bisgaard Magne +7 more
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Toxins, 2011 Aggregatibacter actinomycetemcomitans has been described as a member of the indigenous oral microbiota of humans, and is involved in the pathology of periodontitis and various non-oral infections. This bacterium selectively kills human leukocytes through
Anders Johansson, Johansson Anders
exaly +5 more sources
Immunogenicity and protective efficacy of seven candidate vaccines boosted with recombinant proteins, whole-cell bacterins of three serotypes of Mannheimia haemolytica, and an emulsion-type adjuvant [PDF]
Frontiers in Veterinary ScienceIntroductionMannheimia haemolytica is a primary cause of bovine respiratory disease, leading to substantial economic losses in the livestock industry.
Aslı Balevi +4 more
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Periodontology 2000, EarlyView., 2023 Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis +5 more
wiley +1 more source
The Iraqi Journal of Veterinary Medicine, 2012 This study was conducted to extract and titrate the leukotoxin of Fusobacterium necrophorum isolates recovered from 75abscesses found in 24 livers of slaughtered cattle in Sulaimaniyah region.
Suha Ali Hussein
doaj +3 more sources
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source