Results 11 to 20 of about 3,055 (179)
Evolution of the leukotoxin promoter in genus
BMC Evolutionary Biology, 2009 Background The Mannheimia species encompass a wide variety of bacterial lifestyles, including opportunistic pathogens and commensals of the ruminant respiratory tract, commensals of the ovine rumen, and pathogens of the ruminant integument.
Bisgaard Magne +7 more
doaj +6 more sources
Therapeutic Applications of Aggregatibacter actinomycetemcomitans Leukotoxin
PathogensAggregatibacter actinomycetemcomitans is a Gram-negative oral bacterium that has been primarily studied for its role in causing periodontal disease. The bacterium has also been implicated in several systemic diseases such as endocarditis and soft tissue ...
Scott C. Kachlany, Brian A. Vega
doaj +3 more sources
Periodontology 2000, EarlyView., 2023 Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis +5 more
wiley +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Toxins, 2020 Leukotoxins are the critical virulence factors of several Gram-positive and Gram-negative bacteria [...]
openaire +3 more sources
BMC Infectious Diseases, 2011 Background Chronic infections and associated inflammatory markers are suggested risk factors for cardiovascular disease (CVD). The proinflammatory cytokine, interleukin (IL)-1β, is suggested to play a role in the regulation of local inflammatory ...
Jansson Jan-Håkan +6 more
doaj +1 more source
A fast and simple assay to quantify bacterial leukotoxin activity
Electronic Journal of Biotechnology, 2016 Background: Mannheimia haemolytica is the primary bacterial pathogen in causing bovine respiratory disease with tremendous annual losses in the cattle industry. The leukotoxin from M. haemolytica is the predominant virulence factor.
Tobias Oppermann +3 more
doaj +1 more source
Frontiers in Veterinary Science, 2021 We evaluated the efficacy of three vaccine formulations containing different combinations of proteins (43K OMP, leukotoxin recombinant protein PL4 and hemolysin recombinant protein H2) and killed whole cell Fusobacterium necrophorum in preventing liver ...
Jiawei Xiao +7 more
doaj +1 more source
Identification and characterization of the Pasteurella haemolytica leukotoxin [PDF]
Infection and Immunity, 1987 The identification and chromatographic characterization of the leukotoxin of Pasteurella haemolytica is described. The toxin, which has an apparent native molecular weight of greater than 400,000 as judged by gel exclusion chromatography, has a 105-kilodalton (105K) polypeptide as its major protein component.
Y F, Chang +3 more
openaire +2 more sources
Aggregatibacter Actinomycetemcomitans – A Tooth Killer? [PDF]
Journal of Clinical and Diagnostic Research, 2014 Strong evidence is available on Aggregatibacter actinomycetemcomitans (A.a) on its role as the causative agent of localised juvenile periodontitis (LJP), a disease characterised by rapid destruction of the tooth-supporting tissues.
Manoj Raja, Fajar Ummer, C.P Dhivakar
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