Results 21 to 30 of about 2,921 (175)
Leukotoxins are the critical virulence factors of several Gram-positive and Gram-negative bacteria [...]
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Biological and molecular characterization of a sheep pathogen isolate of Mannheimia haemolytica and leukotoxin production kinetics [PDF]
Background and Aim: Mannheimia haemolytica (Mha) is a common agent of pneumonia in ruminants globally, causing economic losses by morbidity, mortality, and treatment costs.
Dounia Bkiri +10 more
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Leukotoxic activity of Aggregatibacter actinomycetemcomitans and periodontal attachment loss. [PDF]
Aggregatibacter actinomycetemcomitans is a Gram-negative periodontitis-associated bacterium that expresses a toxin that selectively affects leukocytes.
Carola Höglund Åberg +4 more
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Plasma Linoleate Diols Are Potential Biomarkers for Severe COVID-19 Infections
Polyunsaturated fatty acids are metabolized into regulatory lipids important for initiating inflammatory responses in the event of disease or injury and for signaling the resolution of inflammation and return to homeostasis. The epoxides of linoleic acid
Cindy B. McReynolds +13 more
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β-Hemolysis May Not Be a Reliable Indicator of Leukotoxicity of Mannheimia haemolytica Isolates
Mannheimia (Pasteurella) haemolytica causes bronchopneumonia in domestic and wild ruminants. Leukotoxin is the critical virulence factor of M. haemolytica. Since β-hemolysis is caused by a large number of leukotoxin-positive M. haemolytica isolates,
Jegarubee Bavananthasivam +5 more
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Background Chronic infections and associated inflammatory markers are suggested risk factors for cardiovascular disease (CVD). The proinflammatory cytokine, interleukin (IL)-1β, is suggested to play a role in the regulation of local inflammatory ...
Jansson Jan-Håkan +6 more
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Monoclonal antibodies to leukotoxin of Actinobacillus actinomycetemcomitans [PDF]
Hybridoma cell lines which produce monoclonal antibodies to a leukotoxin from Actinobacillus actinomycetemcomitans were prepared. The monoclonal antibodies were selected for their ability to neutralize the cytotoxic activity of the leukotoxin and recognize the toxin on nitrocellulose blots. The antibodies belonged to either the immunoglobulin G1 (IgG1)
J M, DiRienzo +4 more
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A fast and simple assay to quantify bacterial leukotoxin activity
Background: Mannheimia haemolytica is the primary bacterial pathogen in causing bovine respiratory disease with tremendous annual losses in the cattle industry. The leukotoxin from M. haemolytica is the predominant virulence factor.
Tobias Oppermann +3 more
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We evaluated the efficacy of three vaccine formulations containing different combinations of proteins (43K OMP, leukotoxin recombinant protein PL4 and hemolysin recombinant protein H2) and killed whole cell Fusobacterium necrophorum in preventing liver ...
Jiawei Xiao +7 more
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Immunosuppressive properties of Actinobacillus actinomycetemcomitans leukotoxin [PDF]
Actinobacillus actinomycetemcomitans produces a leukotoxin that kills human polymorphonuclear cells (PMNs) and monocytes but not lymphocytes. In this study, we examined A. actinomycetemcomitans leukotoxin for its ability to alter human peripheral blood lymphocyte (HPBL) responsiveness.
G, Rabie, E T, Lally, B J, Shenker
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