Results 21 to 30 of about 3,055 (179)
Monoclonal antibodies to leukotoxin of Actinobacillus actinomycetemcomitans [PDF]
Infection and Immunity, 1985 Hybridoma cell lines which produce monoclonal antibodies to a leukotoxin from Actinobacillus actinomycetemcomitans were prepared. The monoclonal antibodies were selected for their ability to neutralize the cytotoxic activity of the leukotoxin and recognize the toxin on nitrocellulose blots. The antibodies belonged to either the immunoglobulin G1 (IgG1)
J M, DiRienzo +4 more
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Journal of Oral Microbiology, 2015 The expression of the leukotoxin of Aggregatibacter actinomycetemcomitans is regulated by the leukotoxin promoter. A 530-bp deletion or an 886-bp insertion sequence (IS) element in this region has earlier been described in highly leukotoxic isolates ...
Rolf Claesson +4 more
doaj +1 more source
Comparative protection of small ruminants against Mannheimia haemolytica infection by inactivated bacterin and toxoid vaccines [PDF]
Veterinary World, 2023 Background and Aim: Mannheimia haemolytica causes respiratory infection and mortality in sheep and goats, similar to the effects in cattle, which causes major economic damage.
Dounia Bkiri +4 more
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Scientific Reports, 2017 Aggregatibacter actinomycetemcomitans leukotoxin (LtxA) is a major virulence factor that kills leukocytes permitting it’s escape from host immune surveillance. A. actinomycetemcomitans strains can produce high or low levels of toxin.
Vandana Sampathkumar +3 more
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Journal of Indian Society of Periodontology, 2018 Context: Aggregatibacter actinomycetemcomitans (A.a) serotypes may add some important information of the pathogenetic background of periodontal infections. A.a leukotoxin is an important virulence factor in the pathogenesis of periodontal disease and its
Sudhakar Shuntikudege Suprith +3 more
doaj +1 more source
Molecular and phylogenetic study of Staphylococcus aureus isolated from human and cattle of Al-Qadisiyah Governorate, Iraq [PDF]
Veterinary World, 2019 Aim: This study was designed to detect the prevalence of Staphylococcus aureus, to estimate the frequency of methicillin resistance gene (mecA), femA (specific gene for S.
Ahmed Jasim Neamah +4 more
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Immunosuppressive properties of Actinobacillus actinomycetemcomitans leukotoxin [PDF]
Infection and Immunity, 1988 Actinobacillus actinomycetemcomitans produces a leukotoxin that kills human polymorphonuclear cells (PMNs) and monocytes but not lymphocytes. In this study, we examined A. actinomycetemcomitans leukotoxin for its ability to alter human peripheral blood lymphocyte (HPBL) responsiveness.
G, Rabie, E T, Lally, B J, Shenker
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The role of Aggregatibacter actinomycetemcomitans and its leukotoxin in periodontitis
Journal of Oral Microbiology, 2017 Aggregatibacter actinomycetemcomitans is a Gram-negative periodontitis-associated bacterium that expresses a toxin that selectively affects leukocytes. Leukotoxin is encoded by an operon belonging to the core genome of this bacterial species.
Anders Johansson +4 more
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BMC Research Notes, 2012 Background Aggregatibacter actinomycetemcomitans produces a leukotoxin that activates a pro-inflammatory death of human monocytes/macrophages. A specific clone of this bacterium (JP2) has a 530-base pair deletion in the leukotoxin promoter gene and ...
Kwamin Francis +3 more
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Secretion of the Pasteurella leukotoxin by Escherichia coli [PDF]
FEMS Microbiology Letters, 1989 Nucleic acid sequence analysis has indicated that the leukotoxin determinant from Pasteurella haemolytica is related to the hemolysin determinant from E. coli. The cloning and expression in E. coli of the lktCA genes has been previously reported, but the existence of leukotoxin secretory genes equivalent to hlyBD has not been documented. In this report
Y F, Chang +3 more
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