Results 91 to 100 of about 13,074 (114)

Community Agriculture Management in the Gayo Highlands: Integration of Customary and Local Government Authorities

JAKP (Jurnal Administrasi dan Kebijakan Publik)
The research focuses on addressing the challenges associated concerning agricultural management in the Gayo Highlands community, specifically in the Aceh Tengah Regency.
Ikhwan Rahmatika Latif, Ilham Mirza Saputra, Ikhsan Ikhsan, Vellayati Hajad   +3 more
doaj   +1 more source

Penerapan E-Government melalui Aplikasi Masagi Musrenbang di Desa Ciburial

Jurnal Wacana Kinerja
The Ciburial Village Government has developed an innovation in order to make changes to the process of compiling a list of community proposals in the Village Development Planning Deliberation (Musrenbang Desa) process, namely through the Masagi ...
Rodlial Ramdhan Tackbir Abubakar, Dimas Dwi Prasetya   +1 more
doaj   +1 more source

Releasing Brd4 from chromatin by JQ1(+) abolishes the E2-Brd4 interaction on mitotic chromosomes.

, 2013
(A) C33A cells were co-transfected with VN-Brd4 and VC-16E2 and treated with 500 nM JQ1(-) or JQ1(+) at 24h post transfection. Forty-eight hours post-transfection, cells were either fixed immediately (before wash) or washed several times and cultured ...
Ranran Wang (476935), Jianxin You (121729), Christine M. Helfer (476934)   +2 more
core   +1 more source

Supplementary Figures S1-S5 and Legends from AMPK–ULK1-Mediated Autophagy Confers Resistance to BET Inhibitor JQ1 in Acute Myeloid Leukemia Stem Cells

, 2017
Supplementary figure S1. Differential sensitivity of human AML LSCs to JQ1. Supplementary figure S2. Relative levels of the autophagy pathway effectors LC3-II, beclin-1, and pULK1 (S555). Supplementary figure S3. Autophagy induction in KG1 and KG1a cells
Ji Eun Jang (8135850), Ju-In Eom (519760), Yoo Hong Min (8717373), June-Won Cheong (519759), Jung Yeon Lee (12355078), Jin Seok Kim (8717370), Hoi-Kyung Jeung (519761)   +6 more
core   +1 more source

BET Inhibitor JQ1 Attenuates Atrial Fibrillation Through Modulation of Fibrosis, Calcium Homeostasis, and Mitochondrial Function in a Murine Model

Bromodomain and extraterminal domain (BET) proteins act as epigenetic regulators of gene transcription. BET inhibitors have shown therapeutic potential in various models of heart failure; however, their efficacy in atrial fibrillation (AF) remains ...
Murakoshi, Nobuyuki, Ishizu, Tomoko, Aonuma, Kazuhiro, Xu, Dongzhu, Xi, Binyang, Tajiri, Kazuko, Song, Zonghu, Murakata, Yoshiko   +7 more
core   +1 more source

The MYC-independent effects of BET inhibitor JQ1 on super-enhancers in cancer

, 2019
MYC overexpression plays an important role in cancer progression and is a common feature of many cancer types. One reason is due to the invasion of super-enhancer regions by MYC upstream of oncogenes, often resulting in activation of oncogenic pathways ...
Chia, Boon Jun
core  

Inhibidores BET. El singular compuesto (+)-JQ1

, 2015
The serendipitous discovery of (bromodomain extra-terminal) (BET) inhibitors, especially of the BRD4 bromodomain inhibitors, has allowed modulation of gene transcription with epigenetic drugs.
Avendaño, Carmen
core  

Bromodomain Inhibitor JQ1 Modulates Collagen Processing and Ameliorates Bleomycin Induced Dermal Fibrosis in Mice

, 2014
Background/Purpose: Systemic sclerosis (SSc) is a complex pro-inflammatory scarring disease, characterised by elevated deposition of extracellular matrix (ECM) proteins, in particular collagen type I.
Holmes, A, Trinder, S, Shi-Wen, X, Abraham, D, Gilbane, A, Good, A, Tarriela, M   +6 more
core  

Some of the next articles are maybe not open access.

Related searches:

Synergistic Therapy for Cervical Cancer by Codelivery of Cisplatin and JQ1 Inhibiting Plk1-Mutant Trp53 Axis

Nano Letters, 2021
Na Shen, Shuchun Li, Zhilin Liu
exaly  

BET bromodomain inhibitor JQ1 regulates spermatid development by changing chromatin conformation in mouse spermatogenesis

Genes and Diseases, 2022
Mengmeng Sang, Shengnan Gong, Gangcai Xie   +2 more
exaly