Results 71 to 80 of about 13,074 (114)
Arsenic sulfide amplifies JQ1 toxicity via mitochondrial pathway in gastric and colon cancer cells
, 2018 Zhen Tan,* Xiuli Zhang,* Ting Kang, Lian Zhang, Siyu Chen Department of Oncology, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China *These authors contributed equally to this work Purpose: Gastric and colon ...
Tan Z, Kang T, Zhang X, Zhang L, Chen S
core
Kemitraan Pemerintah-Swasta dan Relevansi Terhadap Reformasi Administrasi Negara
JKAP (Jurnal Kebijakan dan Administrasi Publik), 2015 The economic crisis which was experienced by the government of Indonesia in the 1980s has a very significant implication of the reformation of state administration in Indonesia.
Agus Dwiyanto
doaj +1 more source
JQ1 alters epigenomic programming of KSHV latency control region.
, 2017 (A) Schematic of KSHV genome and primer positions a-h used for ChIP assays. (B-H) BCBL1 cells treated with 1% DMSO or 4uM JQ1 for 1 hr were assayed by ChIP for IgG or (B) BRD4, (C) BRD2, (D) CTCF (E) Rad21 (F) RNAPII, (G) H3AcK9, or (H) LANA.
Horng-Shen Chen (473322) +5 more
core +1 more source
State And Modernisation Of Public Administration In Germany
JKAP (Jurnal Kebijakan dan Administrasi Publik), 2015 Setiap negara pada saat ini dihadapkan pada tantangan yang sama yaitu perlunya melakukan modernisasi sistim administmsi.Dalam perkembangan, kesamaan tantanganyang dihadapi tersebut menimbulkan trend dalam melakukan modernisasi sistem administrasi ,yaitu ...
Rainer Pitschas
doaj +1 more source
The BET inhibitor JQ1 targets fat metabolism and counteracts obesity
Introduction: Obesity, one of the most frequent health problems in the adult population, is a condition characterized by excessive white adipose tissue accumulation and accompanied by the increased risk to develop other disorders such as type II diabetes,
Massimo Collino +7 more
core +1 more source
JQ1 reduces oxidative stress-enhanced IL-6 and CXCL8 expression in NHBE cells.
, 2014 NHBE cells pre-treated with JQ1 but not JQ1(-) (both at 5×10−9−10−6 M) reduced IL-1β induced release of IL-6 (A) and CXCL8 (B) in a concentration-dependent manner.
Younis M. Khan (554747) +3 more
core +1 more source
, 2016 The primary aim of this study was to evaluate the antitumor efficacy of the bromodomain inhibitor JQ1 in pancreatic ductal adenocarcinoma (PDAC) patient-derived xenograft (tumorgraft) models.
Council, L. N. +4 more
core +1 more source
, 2022 Die niedermolekulare Verbindung (engl. small molecule) JQ1 hemmt kompetitiv die Bromodomänen der zur bromodomain and extra-terminal domain (BET) Familie gehörenden Proteine BRD2, BRD3 und BRD4, welche als epigenetische Lesedomänen auf die Transkription ...
Schlichting, Jara Pascale
core
[South African Rys., Engine Drawing Card, Sketch No. 6651]
, 1918 This engine drawing card was created for South African Railways, Class 14-38 1/4 F. Section H-14 1/4 F. Sketch 6651.
Baldwin Locomotive Works
core
, 2020 JQ1 is a small-molecule inhibitor of the bromodomain and extra terminal (BET) protein family that potently inhibits the bromodomain testis-specific protein (BRDT), which is essential for spermatogenesis.
Santini, Conrad +5 more
core +1 more source