Results 71 to 80 of about 13,977 (118)

Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity

, 2018
As a potent chemotherapy drug, cisplatin is also notorious for its side-effects including nephrotoxicity in kidneys, presenting a pressing need to identify renoprotective agents.
Yanggang Yuan, Jing Liu, Xinzhou Zhang, Liping Sun, Zheng Dong   +4 more
core   +1 more source

SPM Bidang Kesehatan: Kasus Kabupaten Kulon Progo

JKAP (Jurnal Kebijakan dan Administrasi Publik), 2015
The Minimum Service Standard is a benchmark to measure (assess) the performance of the Local Governments in providing the basic services to the public as the obligatory function of the Local Governments. In addition to this standard, Local Governments in
Agung Kurniawan
doaj   +1 more source

A novel lncRNA MDHDH suppresses glioblastoma multiforme by acting as a scaffold for MDH2 and PSMA1 to regulate NAD+ metabolism and autophagy. [PDF]

J Exp Clin Cancer Res, 2022
He D, Xin T, Pang B, Sun J, Liu ZH, Qin Z, Ji XS, Yang F, Wei YB, Wang ZX, Gao JJ, Pang Q, Liu Q.   +12 more
europepmc   +1 more source

Korupsi APBD: Ekses Negatif Otonomi Daerah (Pentingnya Kebijakan Transparansi Pengelolaan Anggaran dalam APBD)

JKAP (Jurnal Kebijakan dan Administrasi Publik), 2015
This article tries to analyses the negative aspects of the impact of the implementation of decentralisation policy in Indonesia. The author argues that the ill-preparedness of the local governments to carryout the policy such as lack of qualified ...
Yana Karyana
doaj   +1 more source

The BET inhibitor JQ1 targets fat metabolism and counteracts obesity

Introduction: Obesity, one of the most frequent health problems in the adult population, is a condition characterized by excessive white adipose tissue accumulation and accompanied by the increased risk to develop other disorders such as type II diabetes,
Massimo Collino, Claudia Fornelli, Fabio Penna, Giuseppina Caretti, Alessia Sofia Cento, Lorenzo Nevi, Raffaella Mastrocola, Gustavo Ferreira Alves   +7 more
core   +1 more source

JQ1 alters epigenomic programming of KSHV latency control region.

, 2017
(A) Schematic of KSHV genome and primer positions a-h used for ChIP assays. (B-H) BCBL1 cells treated with 1% DMSO or 4uM JQ1 for 1 hr were assayed by ChIP for IgG or (B) BRD4, (C) BRD2, (D) CTCF (E) Rad21 (F) RNAPII, (G) H3AcK9, or (H) LANA.
Horng-Shen Chen (473322), Robert Hills (3685870), Paul M. Lieberman (56113), Zhuo Wang (18668), Alessandra De Leo (3685876), Andrew Kerekovic (3685873)   +5 more
core   +1 more source

Peran Modal Sosial dalam Pelestarian Hutan

JKAP (Jurnal Kebijakan dan Administrasi Publik), 2013
Artikel ini membahas peran modal sosial dalam konservasi hutan di Kabupaten Kampar. Dengan menggunakan metode kualitatif dengan teknik pengumpulan data yaitu observasi, wawancara, dan dokumentasi, artikel ini akan mengungkap bagaimana aspek modal sosial ...
M. Rijal, Syaifullah Noer
doaj   +1 more source

The Bet Bromodomain Inhibitor Jq1 Suppresses Growth Of Pancreatic Ductal Adenocarcinoma In Patient-Derived Xenograft Models

, 2016
The primary aim of this study was to evaluate the antitumor efficacy of the bromodomain inhibitor JQ1 in pancreatic ductal adenocarcinoma (PDAC) patient-derived xenograft (tumorgraft) models.
Council, L. N., Miller, A. L., Gamblin, T. L., Kreitzburg, K. M., Garcia, P. L.   +4 more
core   +1 more source

An Analysis of Poverty Reduction Program Based on the Conditional Cash Transfer (CCT) (A Case of the Family Hope Program Implementation in Pandak Bantul District 2014)

JKAP (Jurnal Kebijakan dan Administrasi Publik), 2016
The study of this research was an analysis of the public policy implementation concerning on the implementation of the Family Hope Program (PKH) in Pandak, Bantul regency in 2014.
Ahmad Hanif
doaj   +1 more source

Facts about Fats: New Insights into the Role of Lipids in Metabolism, Disease and Therapy. [PDF]

Int J Mol Sci, 2020
Segatto M, Pallottini V.
europepmc   +1 more source