Results 61 to 70 of about 13,074 (114)
Purpose: Bromodomain and extraterminal domain (BET) inhibitors are promising epigenetic agents for the treatment of various subsets of acute myeloid leukemia (AML).
민유홍 +4 more
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lBromodomain inhibitor JQ1 reversibly blocks IFN-gamma production
As a class, 'BET' inhibitors disrupt binding of bromodomain and extra-terminal motif (BET) proteins, BRD2, BRD3, BRD4 and BRDT, to acetylated histones preventing recruitment of RNA polymerase 2 to enhancers and promoters, especially super-enhancers, to ...
Mi, Deborah J. +5 more
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Front Matter JKAP (Jurnal Kebijakan dan Administrasi Publik)
Front Matter JKAP (Jurnal Kebijakan dan Administrasi Publik)
Andri Putra Kesmawan
doaj
Modernisasi Aspek Relasional Pemerintah Daerah: Menengok Sejarah, Menatap Masa Depan
The history of Nusantara was since 1600s broken down by the Europeans, so that it has developed not in a "natural" way, in which the governmental style in the independence Indonesia was always in the tendency to centralism, and this has demolished the ...
Samodra Wibawa
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JQ1 suppresses tumor growth via PTEN/PI3K/AKT pathway in endometrial cancer
Overexpression of c-Myc is associated with worse outcomes in endometrial cancer, indicating that c-Myc may be a promising target for endometrial cancer therapy.
Clark, Leslie H. +9 more
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This brief article represent the idea brainstorming and interesting offers on submiting various alternative about the new design of management system of civil servant that proposed by observer and bureaucrats but apparently it can not touch the problems ...
M Nur Budiyanto
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Lian Zhang,1 Yingying Tong,1 Xiuli Zhang,1 Minggui Pan,2,3 Siyu Chen1 1Department of Oncology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Department of Oncology and ...
Zhang X, Zhang L, Tong Y, Chen S, Pan M
core
JQ1 increases BRD4 complex interaction with viral gene promoters.
HeLa cell were infected with HSV-1 at 10 MOI in the absence or presence of 500 nM JQ1 for 6 hr. Protein association and their interaction with viral gene promoters were determined by immunoprecipitation, by immunostaining, and by ChIP assays ...
Ke Ren (34504) +8 more
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Effects of bromodomain and extra-terminal inhibitor JQ1 and interleukin-6 on breast cancer cells
Background: Bromodomain and extra-terminal (BET) proteins are recognized acetylated lysine of histone 4 and act as scaffolds to recruit many other proteins to promoters and enhancers of active genes, especially at the super-enhancers of key genes ...
Jami, Mohammad-Saeid +17 more
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Smart Community Governance Dalam Program Geopark Ngarai Sianok di Kota Bukitting
Smart community governance merupakan suatu konsep dimana masyarakat atau kelompok pintar membantu pemerintah dalam memecahkan masalah. Pariwisata merupakan salah satu keunggulan dari kota Bukittinggi.
Utary Salsabila
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