Results 11 to 20 of about 13,977 (118)
Synthesis and biological profiling of (+)-JQ1 amides as BET inhibitors
, 2021 BET proteini su epigenetski biološki targeti koji regulišu ekspresiju gena i uključeni su u patogenezu kancera. Jedan od inhibitora ovih proteina koji je opisan u literaturi je derivat tienotriazolodiazepina (+)-JQ1.
Koravović, Mladen +6 more
core +5 more sources
Probing BRD inhibition substituent effects in bulky analogues of (+)-JQ1 [PDF]
, 2021 A series of bulky organometallic and organic analogues of the bromodomain (BRD) inhibitor (+)-JQ1 have been prepared. The most potent, N-[(adamantan-1-yl)methyl]-2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.02,6 ...
Joshua Csucker (9444372) +14 more
core +2 more sources
, 2023 The top 10 common genes upregulated or downregulated from 009P1-, 009P2-, (+)-JQ1- and SAHA-treated BCBL-1 cells.
Tran Phuc (3948350) +10 more
core +1 more source
Kebijakan Kriminal Penanggulangan Tindak Pidana Pemerkosan di Transportasi Umum
JKAP (Jurnal Kebijakan dan Administrasi Publik), 2012 Criminal acts involving the perpetration of rape in public transportation vehicles which have become common these day, have caused a lot concern an anxiety in the general public.
Dwi Haryadi
doaj +1 more source
Jurnal Natapraja: Kajian Ilmu Administrasi Negara, 2016 Financially independent for a region is a must in decentralization era. This article try to examine how central and local government push their effort to make a region financially independent.
Lastria Nurtanzila
doaj +1 more source
Jurnal Natapraja: Kajian Ilmu Administrasi Negara, 2019 The purpose of this study is to develop a policy strategy in strengthening the role and function of the East Java Provincial Coordination Board in the context of the effectiveness of the coordination of the implementation of Government and development in
Slamet Hari Sutanto +2 more
doaj +1 more source
Scalable syntheses of the BET bromodomain inhibitor JQ1 [PDF]
, 2015 We have developed methods involving the use of alternate, safer reagents for the scalable syntheses of the potent BET bromodomain inhibitor JQ1. A one-pot three step method, involving the conversion of a benzodiazepine to a thioamide using Lawesson’s ...
Georg, Gunda I. +2 more
core +1 more source
Jurnal Natapraja: Kajian Ilmu Administrasi Negara, 2019 The purpose of this study was to find out how much the level of community satisfaction with public services in urban public sector organizations, namely Cipare Serang Urban Village. The research method used is a quantitative approach.
Ahmad Sururi
doaj +1 more source
, 2019 Programmed cell death ligand 1 (PD-L1) blockade has achieved great success in cancer immunotherapy; however, the response of triple-negative breast cancer (TNBC) to PD-L1 antibodies is limited.
Xiang Liao (628942) +7 more
core +1 more source
MENELISIK KINERJA GOVERNANCE DI DAERAH OTONOMI KHUSUS PAPUA BARAT
Jurnal Natapraja: Kajian Ilmu Administrasi Negara, 2016 The implementation of special autonomy in West Papua province aims to increase the development. Centralized development has brought the people of West Papua in a slump multidimensional.
Ivan Giddeon Fanggidae +2 more
doaj +1 more source