Results 171 to 180 of about 7,223 (244)

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda   +4 more
wiley   +1 more source

Global burden of Klebsiella pneumoniae infections and antimicrobial resistance in 2019. [PDF]

open access: yesBMC Infect Dis
Song HW   +6 more
europepmc   +1 more source

Tunable Synthesis of Multi‐Responsive NH‐Containing Helical Nanographenes With a Chiroptical Switching Function

open access: yesAngewandte Chemie, EarlyView.
The Scholl reaction of 1,3,6,8‐tetrakis(oligophenyl)‐appended carbazoles afforded stable NH‐containing helical nanographenes, which showed significant redshift and reversible on/off switching of CPL upon the addition of base and acid, respectively. Furthermore, excited‐state proton transfer occurred in dimethyl sulfoxide to generate anionic species ...
Chihiro Maeda   +7 more
wiley   +1 more source

A Generative AI-Assisted Piezo-MEMS Ultrasound Device for Plant Dehydration Monitoring. [PDF]

open access: yesAdv Sci (Weinh)
Roy K   +7 more
europepmc   +1 more source

Supramolecular Protection–Deprotection for Switching Pore‐Surface Functionality in a Crystalline Porous Organic Salt

open access: yesAngewandte Chemie, EarlyView.
A supramolecular protection–deprotection strategy temporally separates the framework construction from pore‐surface activation in a porous organic salt. In Form I, phenolic OH groups are protected by DMSO, enabling framework formation. Stepwise single‐crystal‐to‐single‐crystal phase transformation (SCSC) affords a dormant intermediate (Form II ...
Kazuki Shiga   +4 more
wiley   +1 more source

De Novo Discovery of Nonstandard Thioisoindole‐Bridged Bicyclic Peptides Targeting Traf2‐ and NCK‐Interacting Kinase

open access: yesAngewandte Chemie, EarlyView.
An optimized strategy for the ribosomal synthesis of thioisoindole‐bridged bicyclic (TiB) peptides is incorporated into the RaPID platform, enabling high‐throughput discovery from topologically defined TiB libraries. Proof‐of‐concept selection against TNIK identifies nanomolar‐affinity ligands with inhibitory activity, while x‐ray crystallography ...
Yue Zhang   +5 more
wiley   +1 more source

Machine‐Learning‐Guided Discovery of Boron‐Free Narrowband Blue Thermally Activated Delayed Fluorescence Emitters

open access: yesAngewandte Chemie, EarlyView.
A data‐driven discovery engine—exhaustive enumeration of carbazole‐containing polycyclic aromatic hydrocarbons (Cz‐PAHs) followed by machine learning—identifies boron‐free, narrowband blue thermally activated delayed fluorescence emitters for organic light‐emitting diodes (OLEDs).
Masaya Hagai   +6 more
wiley   +1 more source

Development and evaluation of a mechanical chest compression device for standardized rodent cardiopulmonary resuscitation. [PDF]

open access: yesSci Rep
Brixius SJ   +10 more
europepmc   +1 more source

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