Results 131 to 140 of about 2,148,903 (315)

Financial Judge, Administrative Judge

open access: yes, 2010
En tant que juge administratif spécialisé, le juge financier, entendu au sens de la Cour des comptes, des Chambres régionales des comptes et de la Cour de discipline budgétaire et financière, dispose d'une compétence d'attribution. Il lui revient ainsi d’assurer le respect des règles budgétaires et de la comptabilité publique.
openaire   +1 more source

Christina Jacobs v. North Carolina Administrative Office of the Courts, et al. [PDF]

open access: yes, 2015
Floyd, Judge Henry F.   +2 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Artificial Authority: The Promise and Perils of LLM Judges in Healthcare. [PDF]

open access: yesBioengineering (Basel)
Genovese A   +7 more
europepmc   +1 more source

EEOC v. Dolgencorp, LLC dba Dollar General Corporation [PDF]

open access: yes, 2018
Cole,, Judge R. Guy, Jr.   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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