Results 151 to 160 of about 375,781 (313)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

European Community Competition Law- A Rejoinder by Judge Pescatore

open access: yes, 1986
This article contests the contention by Dr. Marenco that Judge Pescatore asserts a theory that Member States of the EED are prevented by Community law from intervening in the marketplace by legislation.
Pescatore, Judge
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Hepatology e-consult responses generated by artificial intelligence demonstrate accuracy but require human oversight. [PDF]

open access: yesHepatol Commun
Huang HKT   +9 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Victor Judge: The Incarnational Art of Flannery O'Connor

open access: yes, 2009
Includes descriptive metadata provided by producer in MPEG-4 video file: "Arts and Culture - Video - Victor Judge: The Incarnational Art of Flannery O'Connor." By Vanderbilt University. Victor Judge, registrar of the Divinity School, speaks on Jan.
Judge, Victor
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Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Judge Osro Cobb papers, 1928-1980

open access: yes
This collection contains correspondence, speeches, published articles, photographs, news clippings, scrapbooks, and other materials relating to the professional, political, and private life of Judge Osro Cobb. It also contains the unpublished manuscript,

core  

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