Results 71 to 80 of about 159,007 (247)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Methodologies for Measuring Judicial Performance: The Problem of Bias
Oñati Socio-Legal Series, 2014 Concerns about gender and racial bias in the survey-based evaluations of judicial performance common in the United States have persisted for decades. Consistent with a large body of basic research in the psychological sciences, recent studies confirm ...
Jennifer Elek, David Rottman
doaj +2 more sources
Judges, Technology and Artificial Intelligence: The Artificial Judge
Law, Technology and HumansChimnomso Elsie Ihedioha reviews Judges, Technology and Artificial Intelligence: The Artificial Judge by Tania Sourdin.
Chimnomso Elsie Ihedioha
doaj +1 more source
Judging the Judges: Evaluating Alignment and Vulnerabilities in LLMs-as-Judges
CoRROffering a promising solution to the scalability challenges associated with human evaluation, the LLM-as-a-judge paradigm is rapidly gaining traction as an approach to evaluating large language models (LLMs). However, there are still many open questions about the strengths and weaknesses of this paradigm, and what potential biases it may hold.
Aman Singh Thakur +4 more
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Workshop : the application of EU competition law by national judges
, 2022 National judges are increasingly becoming the judge of first degree for competition cases in ...
Entrance for national judges 2022 +1 more
core
Article 54 - Judges and Public Officials
Commentary to Article 54 of the 1949 Geneva Convention IV prepared for the Updated ICRC Commentary to the 1949 Geneva Convention IV.
Longobardo, M.
core +3 more sources
Readiness to Use Mediation – Judges’ and Entrepreneurs’ Perspective
Utrecht Law ReviewThe aim of the research is to assess the readiness of Polish judges and entrepreneurs to use mediation. This issue has not yet been the subject of in-depth empirical analysis. Online questionnaire research was carried out on a group of n = 150 judges and
Włodzimierz Broński +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source