Understanding psychiatric-legal disagreements in not criminally responsible on account of mental disorder cases: a gradient boosting model perspective. [PDF]
Front PsycholHaddou A +4 more
europepmc +1 more source
Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform
Advanced Science, EarlyView.We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng +5 more
wiley +1 more source
Mental Illness and Serious Crime: Analysis of the Judicial Response and the Limitations of the Spanish Penitentiary System. [PDF]
Rev Esp Sanid PenitSalmón-Maroto R.
europepmc +1 more source
Advanced Science, EarlyView.We present an organic–inorganic heterostructure transistor array for neuromorphic computing, achieving 95.6% MNIST accuracy and 1.2 fJ per operation, with dynamic spatiotemporal encoding and precise vehicle direction detection under combined optical and electrical stimulation.
Wen‐Min Zhong +13 more
wiley +1 more source
A Child-Centered Framework for Determining Mental Distress Severity and Liability: Evidence from Chinese Judicial Practice. [PDF]
Behav Sci (Basel)Xue Q, Yu D, Zhang Z.
europepmc +1 more source
Advanced Science, EarlyView.A catalytic allosteric DNAzyme assay (SMART) is developed by engineering DNAzyme into a unimolecular biosensor, enabling highly sensitive and multiplex detection of small molecules and nucleic acids. SMART enables extraction‐free, one‐pot, one‐step, isothermal, and cost‐effective detection of biological markers, achieving >95% accuracy for rapid ...
Yanzhe Shen +12 more
wiley +1 more source
International Experience of Damages Compensation in Armed Conflicts: Lessons for Ukraine. [PDF]
F1000ResHartman Y.
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Viruses often hijack host developmental programs to promote infection, but the mechanistic links between reproductive regulation and antiviral immunity remain incompletely understood. Here, we identify a virus‐triggered hierarchical degradation cascade that links antiviral immunity and fertility regulation in rice. We show that the rice grassy
Yuansheng Wu +13 more
wiley +1 more source
The Supreme Court of Canada interprets the fitness to stand trial test in R v. Bharwani. [PDF]
J Forensic SciCurry D, Quinn J.
europepmc +1 more source
Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing
Advanced Science, EarlyView.Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu +7 more
wiley +1 more source