Model‐Informed Evaluation of Hydroxyurea Exposure During Lactation
Hydroxyurea is a cornerstone therapy for sickle cell anemia; however, evidence guiding its use during lactation remains limited. This study aimed to develop a population pharmacokinetic (PK) model to characterize hydroxyurea disposition in maternal plasma and breast milk, and to quantify infant exposure under clinically relevant breastfeeding scenarios.
Anhar Hosawi +5 more
wiley +1 more source
Debate: Young people are living in unprecedented times-too much chaos or too little resilience? Beyond the 'chaos' storyline-Modernising resilience frameworks and mental health care for children and young people in a neurodiversity inclusive digital world. [PDF]
Dray J.
europepmc +1 more source
Harmonizing Social Impact Assessment in the Bioeconomy: A Cross‐Regional Fuzzy‐Delphi Approach
ABSTRACT The bioeconomy transition risks underrepresenting social sustainability, while existing Social Life Cycle Assessment (S‐LCA) applications remain insufficient for comparison and decision support due to heterogeneous and non‐standardized selection of social impact categories. This study proposes a cross‐regional baseline set of impact categories
Julia Lessa Feitosa Virgolino +2 more
wiley +1 more source
Effect of resistance training combined with carbohydrate and protein supplementation on the HOMA-IR, glycemic, lipid profile and hypertrophy of older adults with Type II Diabetes: secondary data analysis of a triple-blind RCT. [PDF]
Rosa JL +9 more
europepmc +1 more source
External Validation of Diagnosis Codes to Identify Pediatric Mental Health Emergency Department Visits for Aggression. [PDF]
Wnorowska JH +3 more
europepmc +1 more source
Fréchet radiomic distance (FRD): A versatile metric for comparing medical imaging datasets. [PDF]
Konz N +18 more
europepmc +1 more source
Can functioning scores guide rehabilitation referral in primary care? Extending ClinFIT to the community level. [PDF]
Ahmedy F +7 more
europepmc +1 more source
Ionization efficiency prediction of electrospray ionization mass spectrometry analytes based on molecular fingerprints and cumulative neutral losses. [PDF]
Nikolopoulos A +5 more
europepmc +1 more source

