Results 91 to 100 of about 85,991 (259)

The Relevance of Curative‐Intent Metastasectomy in Colorectal Cancer Patients: Real‐World Insights From a Certified Comprehensive Cancer Center in Germany

open access: yesInternational Journal of Cancer, EarlyView.
Patients with metastatic colorectal cancer who are ineligible for upfront metastasectomy may still become candidates for secondary metastasectomy with curative intent following response to primary chemotherapy. However, most studies dichotomize metastatic colorectal cancer into resectable and unresectable disease.
Julian W. Holch   +18 more
wiley   +1 more source

Molecular Tumor Boards in Malignant Melanoma: Uncovering Challenges and Opportunities in a Bicenter Retrospective Analysis in Germany

open access: yesInternational Journal of Cancer, EarlyView.
Molecular tumor boards (MTB), interdisciplinary teams that use tumor genomic data to guide personalized treatment decisions, have emerged as a promising strategy in melanoma care, although their real‐world clinical impact remains uncertain. This retrospective study evaluated advanced melanoma patients to assess molecularly guided treatment ...
Glenn Geidel   +26 more
wiley   +1 more source

Diagnóstico clínico e histopatológico de los tumores de los anexos oculares

open access: yesMedisan, 2014
Se realizó un estudio observacional, descriptivo, prospectivo y longitudinal de 92 pacientes con tumores de los anexos oculares, que acudieron a la consulta de Oculoplastia en el Centro Oftalmológico del Hospital General "Dr. Juan Bruno Zayas Alfonso" de
Yailin Audivert Hung   +4 more
doaj  

Unraveling the Plasma Extracellular Vesicles Proteome: Predictors of Resistance in Immunotherapy of Advanced Melanoma

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Despite substantial clinical benefit from immune checkpoint inhibitors (ICI), advanced melanoma remains challenging due to frequent treatment resistance. Resistance may be intrinsic (primary) or emerge over time (secondary). Biomarkers predicting distinct resistance phenotypes before therapy are lacking.
Julian Kött   +17 more
wiley   +1 more source

Host‐specific and deterministic microbiome assembly in major coleopteran stored‐grain pests

open access: yesiMetaOmics, EarlyView.
Dual DNA‐ and RNA‐based sequencing profiled the microbiomes of five major coleopteran stored‐grain pests and their wheat flour substrate. The microbiomes differed significantly among hosts and from flour, yet 11 core bacterial and 9 core fungal taxa were shared across hosts. RNA data revealed host‐specific active microbiota.
Abrar Muhammad   +8 more
wiley   +1 more source

Erratum to Loss of GalNAc-T14 links O-glycosylation defects to alterations in B cell homing in IgA nephropathy. [PDF]

open access: yesJ Clin Invest
Prakash S   +34 more
europepmc   +1 more source

Love and Cause: When Is Biomedically Enhanced Love Desirable?

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT There is a philosophical debate about whether the use of biomedical enhancements to promote or sustain love in romantic relationships is compatible with the desirability of such love. We argue that enhancements are problematic in this respect only if they substantially replace the causal role of the beloved's identity in generating the lover's
Elzė Sigutė Mikalonytė   +2 more
wiley   +1 more source

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