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Hepatitis B virus (HBV) X protein (HBx) is a viral regulatory and multifunctional protein. It is well-known that the canonical HBx reading frame bears two phylogenetically conserved internal in-frame translational initiation codons at Met2 and Met3, thus
Sergio Hernández +5 more
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Dendritic cells (DCs) promote T-cell mediated tolerance to self-antigens and induce inflammation to innocuous-antigens. This dual potential makes DCs fundamental players in inflammatory disorders.
Cristian Doñas +8 more
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Hepatitis B virus (HBV) is an enveloped DNA human virus belonging to the Hepadnaviridae family. Perhaps its main distinguishable characteristic is the replication of its genome through a reverse transcription process. The HBV circular genome encodes only
Rodrigo A. Villanueva, Alejandra Loyola
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Dopaminergic stimulation leads B-cell infiltration into the central nervous system upon autoimmunity
Background Recent evidence has shown dopamine as a major regulator of inflammation. Accordingly, dopaminergic regulation of immune cells plays an important role in the physiopathology of inflammatory disorders.
Carolina Prado +6 more
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The genome streamlining theory suggests that reduction of microbial genome size optimizes energy utilization in stressful environments. Although this hypothesis has been explored in several cases of low-nutrient (oligotrophic) and high-temperature ...
Diego Cortez +5 more
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Since the beginning of 2020, worldwide attention has been focused on SARS-CoV-2, the second strain of the severe acute respiratory syndrome virus.
A. R. Ruiz-Fernández +2 more
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Acidithiobacillus albertensis is an extremely acidophilic, mesophilic, obligatory autotrophic sulfur-oxidizer, with potential importance in the bioleaching of sulfidic metal ores, first described in the 1980s. Here we present the draft genome sequence of
Matías Castro +11 more
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Introdução: O transtorno afetivo bipolar (TAB) é uma condição psiquiátrica complexa, caracterizada por alterações extremas de humor, incluindo episódios de mania e depressão. A relação entre o uso de álcool, drogas e o risco de suicídio em pacientes com
Stéfanie Venturini Fanton +5 more
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Este artigo tem como objetivos apresentar a escritora e poeta polono-israelense Irit Amiel e refletir sobre sua biografia, inseparavelmente unida à sua escrita, em grande parte autobiográfica. Para tanto relato a biografia da escritora por meio de suas palavras, extraídas de livros e entrevistas, e uso estudos a seu respeito.
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Antisense noncoding mitochondrial RNA-2 gives rise to miR-4485-3p by Dicer processing in vitro
Background The antisense noncoding mitochondrial RNAs (ASncmtRNAs) derive from the mitochondrial 16S gene. Knockdown of these transcripts with chemically-modified antisense oligonucleotides induces proliferative arrest, apoptosis and invasiveness ...
Nicole Farfán +4 more
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