Results 21 to 30 of about 1,393,863 (312)

Antisense noncoding mitochondrial RNA-2 gives rise to miR-4485-3p by Dicer processing in vitro

Biological Research, 2021
Background The antisense noncoding mitochondrial RNAs (ASncmtRNAs) derive from the mitochondrial 16S gene. Knockdown of these transcripts with chemically-modified antisense oligonucleotides induces proliferative arrest, apoptosis and invasiveness ...
Nicole Farfán, Nicole Sanhueza, Macarena Briones, Luis O. Burzio, Verónica A. Burzio   +4 more
doaj   +1 more source

GPR43 stimulation on TCRαβ+ intraepithelial colonic lymphocytes inhibits the recruitment of encephalitogenic T-cells into the central nervous system and attenuates the development of autoimmunity

Journal of Neuroinflammation, 2023
Introduction Gut microbiota plays a critical role in the regulation of immune homeostasis. Accordingly, several autoimmune disorders have been associated with dysbiosis in the gut microbiota. Notably, the dysbiosis associated with central nervous system (
Carolina Prado, Alexandra Espinoza, J. Eduardo Martínez-Hernández, Joseph Petrosino, Erick Riquelme, Alberto J. M. Martin, Rodrigo Pacheco   +6 more
doaj   +1 more source

Preclinical evaluation of chimeric antigen receptor T cells targeting the carcinoembryonic antigen as a potential immunotherapy for gallbladder cancer

OncoImmunology, 2023
Gallbladder cancer (GBC) is commonly diagnosed at late stages when conventional treatments achieve only modest clinical benefit. Therefore, effective treatments for advanced GBC are needed.
Ernesto Lopez, Sofía Hidalgo, Eduardo Roa, Javiera Gómez, Carlos Hermansen Truan, Evy Sanders, Cristian Carrasco, Rodrigo Pacheco, Flavio Salazar-Onfray, Manuel Varas-Godoy, Vincenzo Borgna, Alvaro Lladser   +11 more
doaj   +1 more source

VIDAS SEM VIDAS

, 2023
Quando se ama, rega-se a mesma planta, sem arrancar sua flores, cuidando sempre para que ela permaneça bela e seu cheiro inesquecível e único. Quem ama é para sempre, por completar as lacunas deixadas por alguém que se foi, sem deixar rastros ou vestígios do seu paradeiro.
openaire   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Dopamine receptor D3 signalling in astrocytes promotes neuroinflammation

Journal of Neuroinflammation, 2019
Background Neuroinflammation constitutes a pathogenic process leading to neurodegeneration in several disorders, including Alzheimer’s disease, Parkinson’s disease (PD) and sepsis.
Andro Montoya, Daniela Elgueta, Javier Campos, Ornella Chovar, Paulina Falcón, Soledad Matus, Iván Alfaro, María Rosa Bono, Rodrigo Pacheco   +8 more
doaj   +1 more source

Evaluation of the safety and satisfaction of rheumatic patients with accelerated infliximab infusion

Advances in Rheumatology, 2018
Introduction Infliximab infusion generally occurs in 2–4 h. Recent studies have suggested the possibility of accelerated infusion (1 h) of this drug. Objective To evaluate the safety of accelerated infliximab infusion in patients with rheumatic diseases.
Jozélio Freire de Carvalho, Maria Natividade Pereira dos Santos, Joyce Meyre Vieira de Oliveira, Andrea Nogueira S. Lanty Silva, Roberto Paulo Correia de Araujo, Juliana Bahia Cardozo   +5 more
doaj   +1 more source

Health‐related quality of life following total minimally invasive, hybrid minimally invasive or open oesophagectomy: a population‐based cohort study

BJS (British Journal of Surgery), EarlyView., 2020
All patients operated for oesophageal cancer in Sweden from 2013 to April 2018 were identified, and 246 patients were recruited to this population‐based nationwide Swedish study. The results show that longitudinal health‐related quality of life after minimally invasive oesophagectomy was similar to that of the open surgical approach.
F. Klevebro, J. H. Kauppila, S. Markar, A. Johar, P. Lagergren   +4 more
wiley   +1 more source

La vida quotidiana : exploració d'un marc conceptual i d'una proposta d'indicadors [PDF]

, 2006
L'interès per la vida quotidiana ha crescut de manera paral•lela a la necessitat d'augmentar el coneixement racional sobre la realitat social. I, més específicament, si hem de fer cas al que diuen algunes especialistes, aquest interès neix, lligat a la ...
Borràs Català, Vicent, Moreno, Sara, 1978-, Torns, Teresa   +2 more
core   +1 more source

Vidas vividas, vidas escritas

Arquivo Maaravi: Revista Digital de Estudos Judaicos da UFMG, 2023
Este artigo tem como objetivos apresentar a escritora e poeta polono-israelense Irit Amiel e refletir sobre sua biografia, inseparavelmente unida à sua escrita, em grande parte autobiográfica. Para tanto relato a biografia da escritora por meio de suas palavras, extraídas de livros e entrevistas, e uso estudos a seu respeito.
openaire   +1 more source