Results 41 to 50 of about 45,709 (265)
First-Passage Times and Optimal Control of Integrated Jump-Diffusion Processes
Let Y(t) be a one-dimensional jump-diffusion process and X(t) be defined by dX(t)=ρ[X(t),Y(t)]dt, where ρ(·,·) is either a strictly positive or negative function.
Mario Lefebvre
doaj +1 more source
Generalized Telegraph Process with Random Jumps [PDF]
We consider a generalized telegraph process which follows an alternating renewal process and is subject to random jumps. More specifically, consider a particle at the origin of the real line at time t=0. Then it goes along two alternating velocities with opposite directions, and performs a random jump toward the alternating direction at each velocity ...
Di Crescenzo, Antonio +3 more
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Upside and downside correlated jump risk premia of currency options and expected returns
This research explores upside and downside jumps in the dynamic processes of three rates: domestic interest rates, foreign interest rates, and exchange rates.
Jie-Cao He +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The stock price data are sampled at discrete times (e.g., hourly, daily, weekly, etc). When data are sampled at discrete times, they appear as a sequence of discontinuous jump events, even if they have been sampled from a continuous process. On the other
Ali Asghar Movahed, Houshyar Noshad
doaj +1 more source
Jump processes with deterministic and stochastic controls [PDF]
We consider the dynamics of a 1D system evolving according to a deterministic drift and randomly forced by two types of jumps processes, one representing an external, uncontrolled forcing and the other one a control that instantaneously resets the system according to specified protocols (either deterministic or stochastic). We develop a general theory,
Bartlett, Mark S. +2 more
openaire +4 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Reliability Analysis of a Steel Frame
A steel frame with haunches is designed according to Eurocodes. The frame is exposed to self-weight, snow, and wind actions. Lateral-torsional buckling appears to represent the most critical criterion, which is considered as a basis for the limit state ...
M. Sýkora
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source

