Results 191 to 200 of about 1,657,853 (308)

jan./jun. 2019

Tomo, 2019
Expediente Expediente
doaj   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

Systemic immune-inflammation index is associated with diabetic peripheral neuropathy: evidence from NHANES, an external clinical cohort, and exploratory human nerve gene-expression analysis. [PDF]

Front Endocrinol (Lausanne)
Kong C, Gao Z, Jin Q, Zhang Z, Liu J, Kou L, Abudurezhake A, Cai S, Shi G, Zhang L.   +9 more
europepmc   +1 more source

Pulso Semanal (3 jun-7 jun, 2019)

, 2019
Publicación que presenta una síntesis de las principales noticias y sucesos de los mercados financieros y bursátiles del mundo ocurridos en la última semana.
openaire   +1 more source

Super‐Multiplexed Label‐Free Raman Imaging Uncovers Novel Testicular Metabolic Couplings for Residual Body and Spermatogonial Differentiation

Advanced Science, EarlyView.
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li, Xia Chen, Yujuan Qi, Chen Qiao, Qiuru Huang, Dan Zhao, Weiyi Qian, Li Di, Yi Shi, Xiangqi Hu, Yueyue Shao, Kehan Wang, Zhiyu Tang‐Yang, Hanzhi Zang, Yuwen Du, Anran Dong, Jinxiong Feng, Jiayun Chen, Ying Zheng, Xiaofang Tan, Xiaoyu Zhao, Zhonghua Shi, Bo Zheng, Jun Yu   +23 more
wiley   +1 more source

Short-term forecasts and long-term regional scenarios of climate change effects on Swedish forest phenology. [PDF]

Int J Biometeorol
Langvall O, Strandberg G.
europepmc   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

Programmable Chaotic Suspension Electrolysis for Scalable Manufacturing of Vacancy‐Tunable Electrolytic MnO2

Advanced Science, EarlyView.
Programmable chaotic suspension electrolysis bridges laboratory synthesis and industrial manufacturing of high‐performance MnO2 cathodes. This scalable strategy enables tunable oxygen vacancies and a robust γ/β tunnel framework, delivering superior electrochemical performance and thermal stability.
Zhihao Wu, Jie Yang, Yidan Fan, Wentao Li, Jiaxing Li, Jing Guo, Chunbiao Li, Lei Shi, Jiaoyuan Zhang, Xingna Cai, Zukang Chen, Qian Zhang, Jun Du, Changyuan Tao, Qizhi Chen, Guocan Zheng, Zuohua Liu   +16 more
wiley   +1 more source

The Role of AP-1 in Cancer: Regulation, Tumor Microenvironment and Therapeutic Targeting. [PDF]

Biomolecules
Katsianou MA, Vrachas D, Adamopoulos C.
europepmc   +1 more source

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

Advanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao   +10 more
wiley   +1 more source