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DNA Binding Protein Domains

2012
openaire   +1 more source

DNA-Binding Nonhistone Proteins

2019
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DNA Binding Protein Domains

2008
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DBP (DNA binding proteins)

2008
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DNA binding proteins Prediction

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Facilitated diffusion of DNA-binding proteins [PDF]

Physical Review Letters, 2005
The diffusion-controlled limit of reaction times for site-specific DNA-binding proteins is derived from first principles. We follow the generally accepted concept that a protein propagates via two competitive modes, a three-dimensional diffusion in space
A. Jeltsch, Chen-Xu Wu, Holger Merlitz, Jörg Langowski, K. Klenin, Konstantin V. Klenin, M. Ptashne   +6 more
core   +6 more sources

DNA polymerase actively and sequentially displaces single-stranded DNA-binding proteins [PDF]

Nature Communications
Single-stranded DNA-binding proteins (SSBs) protect transiently exposed ssDNA, yet how DNA polymerase (DNAp) displaces them during replication remains unclear.
Longfu Xu, Shikai Jin, Mia Urem, Seung-Joo Lee, Meindert H. Lamers, Xun Chen, Peter G. Wolynes, Gijs J. L. Wuite   +7 more
doaj   +3 more sources

A framework to validate fluorescently labeled DNA-binding proteins for single-molecule experiments [PDF]

Cell Reports: Methods, 2023
Summary: Due to the enhanced labeling capability of maleimide-based fluorescent probes, lysine-cysteine-lysine (KCK) tags are frequently added to proteins for visualization. In this study, we employed an in vitro single-molecule DNA flow-stretching assay
Miranda Molina, Lindsey E. Way, Zhongqing Ren, Qin Liao, Bianca Guerra, Brandon Shields, Xindan Wang, HyeongJun Kim   +7 more
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Blood Plasma Exosomes Contain Circulating DNA in Their Crown

Diagnostics, 2022
It is known that circulating DNA (cirDNA) is protected from nuclease activity by proteins that form macromolecular complexes with DNA. In addition, it was previously shown that cirDNA can bind to the outer surface of exosomes.
Oleg Tutanov, Tatiana Shtam, Alina Grigor’eva, Alexey Tupikin, Yuri Tsentalovich, Svetlana Tamkovich   +5 more
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Single-Molecule Microscopy Meets Molecular Dynamics Simulations for Characterizing the Molecular Action of Proteins on DNA and in Liquid Condensates

Frontiers in Molecular Biosciences, 2021
DNA-binding proteins trigger various cellular functions and determine cellular fate. Before performing functions such as transcription, DNA repair, and DNA recombination, DNA-binding proteins need to search for and bind to their target sites in genomic ...
Kiyoto Kamagata
doaj   +1 more source