Results 21 to 30 of about 1,668,835 (315)

Two time constants for the binding of proteins to DNA from micromechanical data [PDF]

open access: yes, 2000
Recent experimental advances allow the direct measurement of the force/extension behavior for DNA in the presence of strongly binding proteins. Such experiments reveal information about the cooperative mechanism of protein binding.
Turner, Matthew S., Matthew S. Turner
core   +1 more source

Helicase binding to DnaI exposes a cryptic DNA-binding site during helicase loading in Bacillus subtilis [PDF]

open access: yes, 1981
The Bacillus subtilis DnaI, DnaB and DnaD proteins load the replicative ring helicase DnaC onto DNA during priming of DNA replication. Here we show that DnaI consists of a C-terminal domain (Cd) with ATPase and DNA-binding activities and an N-terminal ...
Shi, Wei   +999 more
core   +1 more source

Binding dynamics of a monomeric SSB protein to DNA : a single-molecule multi-process approach [PDF]

open access: yes, 2015
People Programme of the European Union’s Seventh Framework Programme [REA 334496 to B.E.B.]; Leonardo da Vinci European Union Programme (to M.F.G.); Wellcome Trust [099149/Z/12/Z, 091825/Z/10/Z]. Funding for open access charge: Wellcome Trust; University
J. Carlos Penedo   +13 more
core   +1 more source

Divergence of the mRNA targets for the Ssb proteins of bacteriophages T4 and RB69

open access: yesVirology Journal, 2004
The single-strand binding (Ssb) protein of phage T4 (T4 gp32, product of gene 32) is a mRNA-specific autogenous translational repressor, in addition to being a sequence-independent ssDNA-binding protein that participates in phage DNA replication, repair ...
Petrov Vasiliy M   +2 more
doaj   +1 more source

Non-additivity in protein-DNA binding [PDF]

open access: yesBioinformatics, 2005
Localizing protein binding sites within genomic DNA is of considerable importance, but remains difficult for protein families, such as transcription factors, which have loosely defined target sequences. It is generally assumed that protein affinity for DNA involves additive contributions from successive nucleotide pairs within the target sequence. This
Ruadhan A. O'Flanagan   +3 more
openaire   +3 more sources

Versatile toolbox for high throughput biochemical and functional studies with fluorescent fusion proteins [PDF]

open access: yes, 2012
Fluorescent fusion proteins are widely used to study protein localization and interaction dynamics in living cells. However, to fully characterize proteins and to understand their function it is crucial to determine biochemical characteristics such as ...
Sandra B. Hake (165089)   +15 more
core   +1 more source

DNA binding proteins: outline of functional classification

open access: yesBiomolecular Concepts, 2011
DNA-binding proteins composed of DNA-binding domains directly affect genomic functions, mainly by performing transcription, DNA replication or DNA repair.
Zheng Zhiming, Wang Ya
doaj   +1 more source

Identification of DNA-binding proteins using support vector machines and evolutionary profiles

open access: yesBMC Bioinformatics, 2007
Background Identification of DNA-binding proteins is one of the major challenges in the field of genome annotation, as these proteins play a crucial role in gene-regulation.
Gromiha Michael M   +2 more
doaj   +1 more source

Single-stranded DNA binding proteins influence APOBEC3A substrate preference

open access: yesScientific Reports, 2021
The cytidine deaminase, APOBEC3A (A3A), is a prominent source of mutations in multiple cancer types. These APOBEC-signature mutations are non-uniformly distributed across cancer genomes, associating with single-stranded (ss) DNA formed during DNA ...
Amber L. Brown   +5 more
doaj   +1 more source

Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales [PDF]

open access: yes, 2011
Single-stranded DNA binding proteins (SSBs) based on the OB-fold are considered ubiquitous in nature and play a central role in many DNA transactions including replication, recombination and repair.
Kroonin, Eugene V.   +17 more
core   +1 more source

Home - About - Disclaimer - Privacy