Results 41 to 50 of about 5,163,408 (306)
Electrical Probes of DNA-Binding Proteins [PDF]
A DNA electrochemistry platform has been developed to probe proteins bound to DNA electrically. Here gold electrodes are modified with thiol-modified DNA, and DNA charge transport chemistry is used to probe DNA binding and enzymatic reaction both with redox-silent and redox-active proteins.
Barton, Jacqueline K. +3 more
openaire +4 more sources
DNA-binding activity of papillomavirus proteins [PDF]
We demonstrate DNA binding by papillomavirus (PV) open reading frame (ORF) proteins that correspond to the early transforming and trans-activating (E6 and E2) and late structural regions (L2 and L1) from bovine PV type 1 and human PV types 6b and 16.
R G, Mallon +2 more
openaire +2 more sources
Detailed studies of the binding mechanism of the Sinorhizobium meliloti transcriptional activator ExpG to DNA [PDF]
Baumgarth B, Bartels FW, Anselmetti D, Becker A, Ros R. Detailed studies of the binding mechanism of the Sinorhizobium meliloti transcriptional activator ExpG to DNA. Microbiology.
Baumgarth, Birgit +4 more
core +1 more source
Calling cards for DNA-binding proteins [PDF]
Identifying genomic targets of transcription factors is fundamental for understanding transcriptional regulatory networks. Current technology enables identification of all targets of a single transcription factor, but there is no realistic way to achieve the converse: identification of all proteins that bind to a promoter of interest. We have developed
Wang, Haoyi +2 more
openaire +3 more sources
Nuclear factor I genomic binding associates with chromatin boundaries [PDF]
BACKGROUND: The Nuclear Factor I (NFI) family of DNA binding proteins (also called CCAAT box transcription factors or CTF) is involved in both DNA replication and gene expression regulation.
Armelle Gaussin +33 more
core +2 more sources
Functional anatomy of polycomb and trithorax chromatin landscapes in Drosophila embryos. [PDF]
Polycomb group (PcG) and trithorax group (trxG) proteins are conserved chromatin factors that regulate key developmental genes throughout development.
Bernd Schuettengruber +8 more
doaj +1 more source
DNA G-Quadruplex-Binding Proteins: An Updated Overview
DNA G-quadruplexes (G4s) are non-canonical secondary structures formed in guanine-rich sequences. Within the human genome, G4s are found in regulatory regions such as gene promoters and telomeres to control replication, transcription, and telomere ...
Victoria Sanchez-Martin
doaj +1 more source
Protein–DNA binding in high-resolution [PDF]
Recent advances in experimental and computational methodologies are enabling ultra-high resolution genome-wide profiles of protein-DNA binding events. For example, the ChIP-exo protocol precisely characterizes protein-DNA cross-linking patterns by combining chromatin immunoprecipitation (ChIP) with 5' → 3' exonuclease digestion.
Shaun, Mahony, B Franklin, Pugh
openaire +2 more sources
Dimer-dimer stacking interactions are important for nucleic acid binding by the archaeal chromatin protein Alba [PDF]
Archaea use a variety of small basic proteins to package their DNA. One of the most widespread and highly conserved is the Alba (Sso10b) protein. Alba interacts with both DNA and RNA in vitro, and we show in the present study that it binds more tightly ...
Petrovic-Stojanovska, Biljana +4 more
core +1 more source
A novel fibronectin-binding protein from Pasteurella multocida (PM1665) that binds to the fibronectin type III(9-10) modules via two helix-hairpin-helix motifs has recently been described [1].
Lisa M Mullen +7 more
doaj +1 more source

