Results 41 to 50 of about 1,668,835 (315)

Functional anatomy of polycomb and trithorax chromatin landscapes in Drosophila embryos. [PDF]

PLoS Biology, 2009
Polycomb group (PcG) and trithorax group (trxG) proteins are conserved chromatin factors that regulate key developmental genes throughout development.
Bernd Schuettengruber, Mythily Ganapathi, Benjamin Leblanc, Manuela Portoso, Rami Jaschek, Bas Tolhuis, Maarten van Lohuizen, Amos Tanay, Giacomo Cavalli   +8 more
doaj   +1 more source

Urea Denaturation, Zinc Binding, and DNA Binding Assays of Mutant p53 DNA-binding Domains and Full-length Proteins

Bio-Protocol, 2021
In the cell, the thermodynamic stability of a protein – and hence its biological activity – can change dramatically as a result of perturbations in its amino acid sequence and the concentration of stabilizing ligands.
Jeung- Ha, Xin Yu, Darren Carpizo, Stewart Loh   +3 more
doaj   +1 more source

Acrylamide Capture of DNA-Bound Complexes: Electrophoretic Purification of Transcription Factors

BioTechniques, 2002
We have developed a rapid nonradioactive electrophoretic technique to analyze proteins within DNA-binding complexes, acrylamide capture of DNA-binding complexes (ACDC), using Acrydite™-linked DNA-binding targets. The method is highly sensitive and easily
Colleen Nelson, Stephen Hendy, Kim Reid, John Cavanagh   +3 more
doaj   +1 more source

Dimer-dimer stacking interactions are important for nucleic acid binding by the archaeal chromatin protein Alba [PDF]

, 2013
Archaea use a variety of small basic proteins to package their DNA. One of the most widespread and highly conserved is the Alba (Sso10b) protein. Alba interacts with both DNA and RNA in vitro, and we show in the present study that it binds more tightly ...
Petrovic-Stojanovska, Biljana, White, Malcolm F, Jelinska, Clare, Ingledew, W John   +3 more
core   +1 more source

Comparison of histone-like HU protein DNA-binding properties and HU/IHF protein sequence alignment. [PDF]

PLoS ONE, 2017
The structure and function of bacterial nucleoid are controlled by histone-like proteins of HU/IHF family, omnipresent in bacteria and also founding archaea and some eukaryotes.HU protein binds dsDNA without sequence specificity and avidly binds DNA ...
Dmitri Kamashev, Yulia Agapova, Sergey Rastorguev, Anna A Talyzina, Konstantin M Boyko, Dmitry A Korzhenevskiy, Anna Vlaskina, Raif Vasilov, Vladimir I Timofeev, Tatiana V Rakitina   +9 more
doaj   +1 more source

DNA G-Quadruplex-Binding Proteins: An Updated Overview

DNA, 2023
DNA G-quadruplexes (G4s) are non-canonical secondary structures formed in guanine-rich sequences. Within the human genome, G4s are found in regulatory regions such as gene promoters and telomeres to control replication, transcription, and telomere ...
Victoria Sanchez-Martin
doaj   +1 more source

Detailed studies of the binding mechanism of the Sinorhizobium meliloti transcriptional activator ExpG to DNA [PDF]

, 2005
Baumgarth B, Bartels FW, Anselmetti D, Becker A, Ros R. Detailed studies of the binding mechanism of the Sinorhizobium meliloti transcriptional activator ExpG to DNA. Microbiology.
Baumgarth, Birgit, Ros, Robert, Bartels, Frank Wilco, Anselmetti, Dario ; https://orcid.org/, Becker, Anke   +4 more
core   +2 more sources

Pasteurellaceae ComE1 proteins combine the properties of fibronectin adhesins and DNA binding competence proteins.

PLoS ONE, 2008
A novel fibronectin-binding protein from Pasteurella multocida (PM1665) that binds to the fibronectin type III(9-10) modules via two helix-hairpin-helix motifs has recently been described [1].
Lisa M Mullen, Janine T Bossé, Sean P Nair, John M Ward, Andrew N Rycroft, Giles Robertson, Paul R Langford, Brian Henderson   +7 more
doaj   +1 more source

Turnover and function of DNA methylation at transcription factor binding sites [PDF]

, 2014
Cell type identity is largely determined by regulatory networks consistent of various transcription factors. Transcription factor activity requires interaction with DNA and thus critically depends on the accessibility of binding motifs.
Feldmann, Angelika
core   +1 more source

PredPSD: A Gradient Tree Boosting Approach for Single-Stranded and Double-Stranded DNA Binding Protein Prediction

Molecules, 2019
Interactions between proteins and DNAs play essential roles in many biological processes. DNA binding proteins can be classified into two categories. Double-stranded DNA-binding proteins (DSBs) bind to double-stranded DNA and are involved in a series of ...
Changgeng Tan, Tong Wang, Wenyi Yang, Lei Deng   +3 more
doaj   +1 more source