Results 11 to 20 of about 1,668,835 (315)

Expression, purification, and solution-state NMR analysis of the two human single-stranded DNA-binding proteins hSSB1 (NABP2/OBFC2B) and hSSB2 (NAPB1/OBFC2A) [PDF]

, 2021
Single-stranded DNA-binding proteins (SSBs) are essential to all living organisms as protectors and guardians of the genome. Apart from the well-characterized RPA, humans have also evolved two further SSBs, termed hSSB1 and hSSB2. Over the last few years,
Cubeddu, Liza (R16726), Gamsjaeger, Roland (R16936), Teegan Lawson, El-Kamand, Serene (S33745), Lawson, Teegan (S34513), Roland Gamsjaeger, Du Plessis, Mar-Dean (S34302), Mar-Dean Du Plessis, Liza Cubeddu, Serene El-Kamand   +9 more
core   +1 more source

Characterisation of Bombyx mori odorant-binding proteins reveals that a general odorant-binding protein discriminates between sex pheromone components [PDF]

, 2009
In many insect species, odorant-binding proteins (OBPs) are thought to be responsible for the transport of pheromones and other semiochemicals across the sensillum lymph to the olfactory receptors (ORs) within the antennal sensilla.
Field, L.M., Pickett, J. A., Dufour, S. G. L., Zhou, J.J., Keep, N. H., Dufour, Samuel, Field, Linda M., He, X., Hooper, A.M., Hooper, A. M., Pickett, John A., Pickett, J.A., He, Xiaoli, Dufour, S., Field, L. M., Keep, Nicholas H., Robertson, G., Robertson, Giles, Zhou, J-J., Hooper, Antony M., Zhou, Jing-Jiang   +20 more
core   +1 more source

Identification of essential and non-essential single-stranded DNA-binding proteins in a model archaeal organism [PDF]

, 2011
This work is supported by the The Scottish Universities Life Sciences Alliance (SULSA)Single-stranded DNA-binding proteins (SSBs) play vital roles in all aspects of DNA metabolism in all three domains of life and are characterized by the presence of one ...
Skowyra, Agnieszka, Stuart A. MacNeill, Agnieszka Skowyra, MacNeill, Stuart   +3 more
core   +1 more source

Analysis and prediction of single-stranded and double-stranded DNA binding proteins based on protein sequences

BMC Bioinformatics, 2017
Background DNA-binding proteins perform important functions in a great number of biological activities. DNA-binding proteins can interact with ssDNA (single-stranded DNA) or dsDNA (double-stranded DNA), and DNA-binding proteins can be categorized as ...
Wei Wang, Lin Sun, Shiguang Zhang, Hongjun Zhang, Jinling Shi, Tianhe Xu, Keliang Li   +6 more
doaj   +1 more source

Telomeric double-strand DNA-binding proteins DTN-1 and DTN-2 ensure germline immortality in Caenorhabditis elegans

eLife, 2021
Telomeres are nucleoprotein complexes at the ends of chromosomes and are indispensable for the protection and lengthening of terminal DNA. Despite the evolutionarily conserved roles of telomeres, the telomeric double-strand DNA (dsDNA)-binding proteins ...
Io Yamamoto, Kexin Zhang, Jingjing Zhang, Egor Vorontsov, Hiroki Shibuya   +4 more
doaj   +1 more source

Crenarchaeal chromatin proteins Cren7 and Sul7 compact DNA by inducing rigid bends [PDF]

, 2012
Archaeal chromatin proteins share molecular and functional similarities with both bacterial and eukaryotic chromatin proteins. These proteins play an important role in functionally organizing the genomic DNA into a compact nucleoid.
White, Malcolm F., Meng, He, van Noort, John, Noort, S.J.T. van, Schiessel, Helmut, Shahapure, Rajesh, Lanzani, G., Meng, H., Dame, Remus Th, Driessen, R.P.C., Shahapure, R., Suresh, G., Driessen, Rosalie P. C., Lanzani, Giovanni, Suresh, Gorle, Schiessel, H., Dame, R.T., Priyakumar, U. Deva, Priyakumar, U.D., White, M.F.   +19 more
core   +2 more sources

DNA-binding activity of papillomavirus proteins [PDF]

Journal of Virology, 1987
We demonstrate DNA binding by papillomavirus (PV) open reading frame (ORF) proteins that correspond to the early transforming and trans-activating (E6 and E2) and late structural regions (L2 and L1) from bovine PV type 1 and human PV types 6b and 16.
R G, Mallon, D, Wojciechowicz, V, Defendi   +2 more
openaire   +2 more sources

Sequence specificity of single-stranded DNA-binding proteins:a novel DNA microarray approach [PDF]

, 2007
We have developed a novel DNA microarray-based approach for identification of the sequence-specificity of single-stranded nucleic-acid-binding proteins (SNABPs).
Estibeiro, Peter, Heinemann, U., Wear, M.A., Max, K.E., Morgan, Hugh P, Max, Klaas E A, Sadler, P.J., Morgan, H.P., Walkinshaw, M.D., Heinemann, Udo, Walkinshaw, Malcolm D, Wear, Martin A, Gallagher, Maurice P, Cubeddu, L., Sadler, Peter J, Estibeiro, P., Gallagher, M.P., Cubeddu, Liza   +17 more
core   +1 more source

A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA

eLife, 2022
Clamp loaders place circular sliding clamp proteins onto DNA so that clamp-binding partner proteins can synthesize, scan, and repair the genome. DNA with nicks or small single-stranded gaps are common clamp-loading targets in DNA repair, yet these ...
Xingchen Liu, Christl Gaubitz, Joshua Pajak, Brian A Kelch   +3 more
doaj   +1 more source

Calling cards for DNA-binding proteins [PDF]

Genome Research, 2007
Identifying genomic targets of transcription factors is fundamental for understanding transcriptional regulatory networks. Current technology enables identification of all targets of a single transcription factor, but there is no realistic way to achieve the converse: identification of all proteins that bind to a promoter of interest. We have developed
Wang, Haoyi, Johnston, Mark, Mitra, Robi David   +2 more
openaire   +3 more sources