Results 91 to 100 of about 1,005,924 (308)

Numerical simulation of bubble generation in a T-junction [PDF]

, 2012
We present a numerical study of the formation of mini-bubbles in a 2D T-junction by means of the fluid dynamics numerical code JADIM. Numerical simulations were carried out for different flow conditions, giving rise to results on the behavior of bubble ...
S. Arias, D. Legendre, Arias, Santiago, R. González-Cinca, Legendre, Dominique, Gonzales-Cinca, Ricardo   +5 more
core   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Assembling and validating data from multiple sources to study care for Veterans with bladder cancer

BMC Urology, 2017
Background Despite the high prevalence of bladder cancer, research on optimal bladder cancer care is limited. One way to advance observational research on care is to use linked data from multiple sources.
Florian R. Schroeck, Brenda Sirovich, John D. Seigne, Douglas J. Robertson, Philip P. Goodney   +4 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction [PDF]

, 2008
Background: The skeletal neuromuscular junction is a useful model for elucidating mechanisms that regulate synaptogenesis. Developmentally important intercellular interactions at the neuromuscular junction are mediated by the synaptic portion of a basal ...
Fox Michael A, Ho Matthew SP, Fox, Michael, Sanes Joshua R, Sanes, Joshua R, Ho, Matthew S. P., Smyth, Neil, Sanes, Joshua, Smyth Neil, Fox, Michael A., Sanes, Joshua R., Ho, Matthew S.P., Ho, Matthew SP, Michael A Fox, Matthew SP Ho, Neil Smyth, Joshua R Sanes   +16 more
core   +1 more source

Recent progress in enhancing built-in electric fields of perovskite solar cells via junction engineering

Beilstein Journal of Nanotechnology
The performance of perovskite solar cells (PSCs) is primarily governed by the built-in electric field (BEF), which dictates photocarrier separation, drift-diffusion transport, and extraction pathways, thereby shaping critical device parameters such as ...
Tong Xiao, Ke Xu
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Holographic Josephson Junctions

Physical Review Letters, 2011
We construct a gravitational dual of a Josephson junction. Calculations on the gravity side reproduce the standard relation between the current across the junction and the phase difference of the condensate. We also study the dependence of the maximum current on the temperature and size of the junction and reproduce familiar results.
Horowitz, Gary T, Santos, Jorge E, Way, Benson   +2 more
openaire   +5 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source