Results 81 to 90 of about 1,005,924 (308)

GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes [PDF]

, 2014
Processing of Holliday junctions is essential in recombination. We have identified the gene for the junction-resolving enzyme GEN1 from the thermophilic fungus Chaetomium thermophilum, and expressed the N-terminal 487 amino acid section. The protein is a
Lilley, David M. J., Déclais, Anne-Cécile; id_orcid, Lilley, David M. J.; id_orcid, Gartner, Anton, Liu, Yijin, Freeman, Alasdair D. J., Declais, Anne-Cecile   +6 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Junction, Land of living waters in the delightful Hill Country of Texas.

, 1930
This pamphlet describes the city of Junction, its history, businesses, natural resources, and public works.Title from front and back panels. 'For any further information ... write to the Chamber of Commerce, Junction, Texas'--page 9. Front and back panel
Unknown
core  

Diffusion Analysis and Impact of RTA on Strained Phosphorous-Doped Si for Advanced SOI Nodes

IEEE Journal of the Electron Devices Society
Improvement of source/drain regions is necessary to meet the requirements of advanced Fully Depleted Silicon On Insulator (FD-SOI) nodes. The implementation and control of in-situ doped epitaxy while optimizing the dopant diffusion close to the channel ...
Theo Cabaret, Eva Dos Reis, Valerie Lapras, Nicolas Gauthier, Joel Kanyandekwe   +4 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Cave Junction Notice of Adopted Amendment (2010-09-03)

, 2010
14 pp. Adopted 2010-09-03. Department of Land Conservation and Development Notice of Adopted AmendmentThe City of Cave Junction amended and four titles of the Municipal Code with the adoption of four ordinances: Title 12: to require sidewalk width to be ...
Cave Junction (Or.)
core   +1 more source

Building Blood Vessels—One Rho GTPase at a Time

Cells, 2019
Blood vessels are required for the survival of any organism larger than the oxygen diffusion limit. Blood vessel formation is a tightly regulated event and vessel growth or changes in permeability are linked to a number of diseases.
Haley Rose Barlow, Ondine Cleaver
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Water surface topology of supercritical junction flow

Journal of Hydrology and Hydromechanics, 2019
The complexity of flow conditions at junctions amplifies significantly with supercritical flow. It is a pronounced three-dimensional two-phased flow phenomenon, where standing waves with non-stationary water surface are formed.
Rak Gašper, Hočevar Marko, Steinman Franci   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source