Results 91 to 100 of about 711,479 (294)
The Criminal Jury, Moral Judgments, and Political Representation [PDF]
, 2018 Was the sexual act consensual? Did the defendant have a reasonable belief that he was in imminent danger of death by an attacker? Did the police use excessive force? Did the defendant act in a heinous or cruel manner?
Lee, Youngjae
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
What is special about the proportion? A research report on special majority voting and the classical Condorcet jury theorem [PDF]
It is known that, in Condorcet’s classical model of jury decisions, the proportion of jurors supporting a decision is not a significant indicator of that decision’s reliability: the probability that a particular majority decision is correct given the ...
Christian List
core
Rhode Island Report on the Judiciary 2003 [PDF]
, 2003 As I near the completion of my first year as State Court Administrator, it is with both pleasure and pride that, pursuant to G.L. 1956 (1997 Reenactment) § 8-15-7,1 submit the 2003 Annual Report on the Rhode Island Judiciary.
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
A Comparison of Criminal Jury Decision Rules in Democratic Countries [PDF]
, 2007 This paper furnishes jury system information about the twenty-eight democracies (excluding the United States) that have been consistently democratic since at least the early 1990s and have a population of five million people or more (with allowance for ...
Leib, Ethan J.
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Forms of aleatory democracy: genesis and development
Антиномии, 2018 The article analyzes forms of citizen participation in public decision-making as alternative to traditional institutions of citizen participation (public discussions of draft laws, public hearings, citizen participation in public councils formed by ...
Viktor N. Rudenko
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source