Results 91 to 100 of about 632,340 (320)

Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data

open access: yesBioinform., 2011
Motivation: High-throughput sequencing (HTS) technologies have made low-cost sequencing of large numbers of samples commonplace. An explosion in the type, not just number, of sequencing experiments has also taken place including genome re-sequencing ...
T. Carver   +4 more
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

De autonijverheid in België [PDF]

open access: yes
This paper provides an extensive overview of the economic importance and evolution of the car manufacturing industry. In addition, it provides evidence that the car industry is still playing a vital role in process innovation.
François Coppens, George Van Gastel
core  

T-Cell Receptor Cognate Target Prediction Based on Paired α and β Chain Sequence and Structural CDR Loop Similarities

open access: yesFrontiers in Immunology, 2019
T-cell receptors (TCR) mediate immune responses recognizing peptides in complex with major histocompatibility complexes (pMHC) displayed on the surface of cells.
Esteban Lanzarotti   +2 more
semanticscholar   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Dynamic Clusters [PDF]

open access: yes, 2007
Globalization has had an enormous impact on traditional industrial structures. It seems almost the case that everything is everywhere the same. And yet, in reality, some regions in a single industrialized country enjoy rapid economic growth while others ...
Falck, Oliver, Heblich, Stephan
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Management control of supplier relationships in manufacturing: a case study in the automotive industry. [PDF]

open access: yes
This paper studies management control design of supplier relationships in manufacturing, a supply chain phase currently under-explored. Compared to supplier relations during procurement and R&D, which research found to be governed by a combination of ...
Pernot, Eli, Roodhooft, Filip
core  

Gazdaságfejlesztés az ingolstadti járműipari központban = Economic development in the Ingolstadt automotive center [PDF]

open access: yes, 2014
Territorial and regional structures are tightly linked to economic development. The example of automotive industry as a driver for economic development, and its distinctive presence in the Central-Eastern European region explains why we should examine ...
Fekete, Dávid
core  

The Effect of Sample Bias and Experimental Artefacts on the Statistical Phylogenetic Analysis of Picornaviruses

open access: yesViruses, 2019
Statistical phylogenetic methods are a powerful tool for inferring the evolutionary history of viruses through time and space. The selection of mathematical models and analysis parameters has a major impact on the outcome, and has been relatively well ...
Yulia Vakulenko   +2 more
doaj   +1 more source

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