Results 121 to 130 of about 2,720,288 (295)
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Corrigendum to "Towards a theory of just transition: A neo-Gramscian understanding of how to shift development pathways to zero poverty and zero carbon" [Energy Res. Soc. Sci. 70 (2020) 101789]. [PDF]
Winkler H.
europepmc +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Shaping tomorrows: the CCS as agents of change in Europe’s transition
This article explores the role of the Cultural and Creative Sectors (CCS) as systemic enablers of the European Union’s (EU) triple transition—green, digital and just.
Eva De Smedt, Isabelle De Voldere
doaj +1 more source
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Just Transition for China’s Coal Regions Towards Carbon Neutrality Targets
China has pledged to peak its carbon emissions before 2030 and achieve carbon neutrality by 2060. A crucial aspect of this commitment involves transitioning from coal‐dependent activities primarily concentrated in certain regions pivotal to local ...
Ying Zhang +3 more
doaj +1 more source
Economic Reforms and Constitutional Transition [PDF]
This paper investigates the relationship between economic reforms and constitutional transition, which has been neglected by many transition economists.
Jeffrey D. Sachs +2 more
core
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source

