Results 91 to 100 of about 2,077,233 (302)

Августинова теорија праведног рата

open access: yesGodišnjak, 2015
Augustine is usually credited as the founder of the theory of just war in Christianity. This theory was defined in the time when Roman Empire was in retreat in front of the barbarians and when Church was struggling against heretics.
Miloš Jelić
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Displacement as Significant Collateral Harm in War

open access: yesGlobal justice: Theory, Practice, Rhetoric, 2018
Traditionally, in deciding whether some strategy or action in war is proportionate and necessary and thus permissible both international law and just war theory focus exclusively on civilian deaths and the destruction of civilian infrastructure.
Jovana Davidovic
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Putting the War Back in Just War Theory: A Critique of Examples [PDF]

open access: yes, 2017
Analytic just war theorists often attempt to construct ideal theories of military justice on the basis of intuitions about imaginary and sometimes outlandish examples, often taken from non-military contexts. This article argues for a sharp curtailment of
Mark, Rigstad
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Someter Al Enemigo Sin Librar Combate

open access: yesRevista de Estudios Sociales, 2003
This article intends to investigate the meaning of war in a Chinese text wrote more than 300 years ago: The Art of War, by Sun Tzu. The essay uses Mao Tse Tung difference between "just wars" and "unjust wars", to ask about the origin of the "just war ...
Jaime Barrera Parra
doaj  

Beyond the Battlefield: The Park That Once Was Stevens’s Furnace

open access: yes, 2016
If you’re a frequent reader of the Compiler, it comes as no news to you that the Gettysburg area is historic for more than just its battlefield. From a pre-war African American community to the World War I tank camp commanded by a young Dwight Eisenhower,
Lavery, Kevin P.
core  

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