Results 101 to 110 of about 2,077,233 (302)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Just war theory and scapegoat mechanism: An analysis of missio Dei and social order
HTS Teologiese Studies/Theological StudiesThis article examined Augustine’s just war theory through René Girard’s scapegoat mechanism, as posited in his theory of mimetic desire. Augustine, in his development of just war theory, adopted a realist approach to justify the ethical criteria for ...
Godfrey T. Baleng
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Just War and the Indian Tradition: Arguments from the Battlefield [PDF]
, 2019 A famous Indian argument for jus ad bellum and jus in bello is presented in literary form in the Mahābhārata: it involves events and dynamics between moral conventionalists (who attempt to abide by ethical theories that give priority to the good) and ...
Ranganathan, Shyam
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Diario de Irak: A Just War or Just War?
Theory In Action, 2009 This study examines Mario Vargas Llosa’s trip to Iraq in 2003 and his conclusions regarding the rationales for the U. S.-led occupation. Vargas Llosa observes that the war was initiated under false pretenses, and that the Iraqi people are frustrated with the chaos and instability.
openaire +2 more sources
Remembrance Day: History, Memory and the 20th Maine
, 2017 Every November, on the Saturday closest to the 19th, the town of Gettysburg celebrates Remembrance Day. This day is held in memory of those who fought and died at the Battle of Gettysburg and during the Civil War as a whole.
Labbe, Savannah A.
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Who Fought Just War? Walzer’s Theory and the War in the Former Yugoslavia
Međunarodne Studije, 2015 Applying Walzer’s theory, this article analyzes the morality of the war in the former Yugoslavia. The main findings are the following: Serbia fought an unjust war during the entire 1991-99 period.
Miljenko Antić
doaj