Results 121 to 130 of about 2,077,233 (302)

The End is Near: The Civil War in 1864

open access: yes, 2015
In the minds of most Civil War lovers, the year 1864 marks the noticeable shift from a conciliatory war to a hard war. Most view it through the lens of Ulysses S. Grant’s Overland Campaign, through William Tecumseh Sherman’s March to the Sea, through the
Kirk, Brianna E.
core  

The Relevance of Just War Theory [PDF]

open access: yes, 2010
Conflict is a part of life. Since conflict is always opened to become worse and engage violence, Just War will remain taking place in any discussion about ...
Santosa, Nyong Eka Teguh Iman
core  

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Shakespearean Histories and Greek History: Henry V and Richard II at the Greek National Theatre (1941, 1947) [PDF]

open access: yes, 2007
Henry V and Richard II made their first and only appearance on the Greek stage in the turbulent 1940s. The first was performed in March 1941, just before the arrival of the German nazis, and the second in November 1947, a year after the problematic ...
Krontiris, Tina
core  

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Kořeny teorie spravedlivé války: od Platóna ke Grotiovi

open access: yesTheatrum Historiae, 2008
The so-called “just war theory” is one of the few instances in the history of human endeavors when organized violence (i.e. war) directly meets philosophy.
Jiří Hutečka
doaj  

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