Results 91 to 100 of about 8,429,797 (274)
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Who Fought Just War? Walzer’s Theory and the War in the Former Yugoslavia
Applying Walzer’s theory, this article analyzes the morality of the war in the former Yugoslavia. The main findings are the following: Serbia fought an unjust war during the entire 1991-99 period.
Miljenko Antić
doaj
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
The Vietnam War and the laws of war: An examination of North Vietnam's military strategy and its compliance with the laws of war. [PDF]
The thesis focuses on the Vietnamese side of the Vietnam War. Though this war is one of the wars best documented, literature about the Vietnamese side is much less in comparison with that about the American side.
Le, Hai Van
core +2 more sources
This article evaluates Israel’s military operations in Gaza from 2023 to 2024 through the lens of Just War Theory (JWT), focusing on both the justification for war (jus ad bellum) and conduct in war (jus in bello).
Baston Kondowe, Broto Wardoyo
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source
Rivers and Lakes: Zhuangzi’s Critique of Just War and the Zhuangzian War Ethics and Peace Strategy
Just war theory, significantly shaped by Christian moral theology, has provided a prominent ethical framework for discussions on the justice of war. Numerous works have been published on classical Chinese counterparts, including passages from the Mengzi,
Ting-mien Lee
doaj +1 more source

