Results 71 to 80 of about 35,837 (295)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The Chinese Meaning of Just War and Its Impact on the Foreign Policy of the People’s Republic of China [PDF]
The image of China’s peaceful rise, which the Chinese government is keen to enforce in the world, stands in contrast to the view of China’s ascent as a threat.
Nadine Godehardt
core
, 2021 The ancient philosophy of Stoicism, itself one of the foundations for international law, can improve contemporary just war thinking by forming a coherent set of philosophical principles to serve as a foundation for a just war theory.
Konstantakos, Leonidas D
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Displacement as Significant Collateral Harm in War
Global justice: Theory, Practice, Rhetoric, 2018 Traditionally, in deciding whether some strategy or action in war is proportionate and necessary and thus permissible both international law and just war theory focus exclusively on civilian deaths and the destruction of civilian infrastructure.
Jovana Davidovic
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The Vietnam War and the laws of war: An examination of North Vietnam's military strategy and its compliance with the laws of war. [PDF]
, 2011 The thesis focuses on the Vietnamese side of the Vietnam War. Though this war is one of the wars best documented, literature about the Vietnamese side is much less in comparison with that about the American side.
Le, Hai Van
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Public and private just wars: Distributed cyber deterrence based on Vitoria and Grotius
Internet Policy Review, 2020 This contribution discusses the growing importance of cyber attacks directed at the public sphere and the crucial role of non-state actors in cyber attacks from a perspective of just war theory.
Johannes Thumfart
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source