Results 61 to 70 of about 35,837 (295)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Counting animals in war : first steps towards an inclusive just-war theory [PDF]
, 2021 War is harmful to animals, but few have considered how such harm should affect assessments of the justice of military actions. In this paper, we propose a way in which concern for animals can be included within the just-war framework, with a focus on ...
Josh Milburn (12048914) +3 more
core +1 more source
Just war theory and scapegoat mechanism: An analysis of missio Dei and social order
HTS Teologiese Studies/Theological StudiesThis article examined Augustine’s just war theory through René Girard’s scapegoat mechanism, as posited in his theory of mimetic desire. Augustine, in his development of just war theory, adopted a realist approach to justify the ethical criteria for ...
Godfrey T. Baleng
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Missionalia: Southern African Journal of Missiology, 2019 Three wars stand out In Zimbabwean historiography with regards to the use and application of the just war tradition. The first was occasioned by the murder of Fr Gonzalo Da Silveira, a Portuguese Jesuit missionary, in 1560.
Gundani, Paul
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Jihād as Defense: Just-war theory in the Quran and Sunnah [PDF]
, 2016 The mainstream view of jihād in Islam is consistent with modern international norms of non-violence. The Quran and Sunnah permit Muslims to defend themselves from aggression, while also limiting warfare to the purpose of preserving security, freedom ...
Parrott, Justin
core
Soldiers and ‘respect’ in complex conflicts: an Afghan case
Etikk i Praksis: Nordic Journal of Applied Ethics, 2017 This paper discusses the meaning of ‘respect’ in complex conflicts and aims to be a contribution to thinking about ethics in war along with the Just War tradition. The point of departure is the increased focus on soldiers as moral decision-makers in war,
Cornelia Vikan
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source