Results 41 to 50 of about 35,885 (283)

İbn Miskeveyh'in adalet düşüncesinin bireysel ve toplumsal boyutları

, 2021
The 10th-century philosopher Ibn Miskawayh is a philosopher of the tradition of Islamic philosophy who influenced many philosophers who came after him with his contribution to moral thought.
Bayram, Elif
core  

Developing and validating a culturally grounded scale of indigenous leadership competencies: Evidence from Maya-Mam and Xinka communities in Guatemala

Advancements in Agricultural Development
Indigenous communities in Guatemala face persistent social, economic, and political inequities that limit their participation in development decision-making, including agricultural and rural development initiatives.
Pablo Lamino, Amy E. Boren-Alpízar, Scott Burris, Jason Headrick, Carlos E. Carpio   +4 more
doaj   +1 more source

BEST PRACTICES TO ACHIEVING PEACE JUSTICE AND STRONG INSTITUTIONS (SDG 16)

EPRA International Journal of Multidisciplinary Research (IJMR), 2022
Low socio-economic development can support the conditions for social violence and conflict, but it is also a consequence of violence and conflict. Through Goal 16, the SDGs recognize the long reaching consequences of conflict and violence for development outcomes.
null ALiyu M. Sule, null Jemimah Nathaniel   +1 more
openaire   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

“Is Restorative Justice Greek to Me?” : Exploring Its Applicability in Greek Youth Detention Centres

, 2021
Justice systems around the world are constantly working to balance reform/rehabilitation/re-entry and punishment in response to juvenile delinquency. In recent years, there has been a strong emphasis on the notion of restorative justice as an alternative
Stamatakis, Nikolaos,
core   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Legal Institutions and Financial Development [PDF]

Why do some countries have growth-enhancing financial systems, while others do not? Why have some countries developed the necessary investor protection laws and contract-enforcement mechanisms to support financial institutions and markets, while others ...
Thorsten Beck, Ross Levine
core   +4 more sources

U.S. state libraries as strong institutions: Supporting justice for LGBTQ+ patrons?

Proceedings of the Association for Information Science and Technology, 2020
AbstractOne hundred and ninety‐three countries have ratified the United Nations 2030 Agenda for Sustainable Development outlining 17 goals to promote prosperity of people and the planet in a peaceful and sustainable way. Despite hate crimes and marginalization around the world, LGBTQ+ communities are missing from conceptualization and description of ...
Joseph Winberry, Bharat Mehra
openaire   +2 more sources