Results 11 to 20 of about 1,782 (159)

In Vivo Analysis of Angle Dysgenesis in Primary Congenital, Juvenile, and Adult-Onset Open Angle Glaucoma

, 2017
Viney Gupta, Abadh K. Chaurasia, Shikha Gupta, Bhavya Gorimanipalli, Ajay Sharma, Amisha Gupta   +5 more
openalex   +3 more sources

Genes of the unfolded protein response pathway harbor risk alleles for primary open angle glaucoma. [PDF]

PLoS ONE, 2011
The statistical power of genome-wide association (GWA) studies to detect risk alleles for human diseases is limited by the unfavorable ratio of SNPs to study subjects.
Mary Anna Carbone, Yuhong Chen, Guy A Hughes, Robert N Weinreb, Norman A Zabriskie, Kang Zhang, Robert R H Anholt   +6 more
doaj   +1 more source

Exome sequencing identifies procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 mutations in primary congenital and juvenile glaucoma

Indian Journal of Ophthalmology, 2021
Purpose: To report the association of procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 (PLOD2) mutations with bilateral primary congenital glaucoma (PCG) in monozygotic twins and with nondominant juvenile-onset primary open-angle glaucoma (JOAG ...
Viney Gupta, Bindu I Somarajan, Gagandeep Kaur, Shikha Gupta, Renu Singh, Dibyabhaba Pradhan, Harpreet Singh, Punit Kaur, Anshul Sharma, Bindia Chawla, Anisha Pahuja, Rajesh Ramachandran, Arundhati Sharma   +12 more
doaj   +1 more source

Gonioscopy-assisted transluminal trabeculotomy for open-angle glaucoma with failed incisional glaucoma surgery: two-year results

BMC Ophthalmology, 2023
Background To evaluate the safety and efficacy of gonioscopy-assisted transluminal trabeculotomy (GATT) in treating patients with open-angle glaucoma (OAG) who had failed prior incisional glaucoma surgery.
Yiwei Wang, Weijia Zhang, Chen Xin, Jinghong Sang, Yang Sun, Huaizhou Wang   +5 more
doaj   +1 more source

A rare optineurin mutation in an Indian family with coexistence of JOAG and PCG

Indian Journal of Ophthalmology, 2023
Purpose: This study focused on the genetic screening of Myocilin (MYOC), Cytochrome P450 family 1 subfamily B member 1 (CYP1B1), Optineurin (OPTN), and SIX homeobox 6 (SIX6) genes in a family with coexistence of primary congenital glaucoma (PCG) and ...
Manoj Yadav, Anshu Yadav, Aarti Bhardwaj, Chand Singh Dhull, Sumit Sachdeva, Ritu Yadav, Mukesh Tanwar   +6 more
doaj   +1 more source

Estimating the age of the p.Cys433Arg variant in the MYOC gene in patients with primary open-angle glaucoma. [PDF]

PLoS ONE, 2018
The aim of this study was to estimate the age of the Cys433Arg (c.1297T>C, p.Cys433Arg) variant by comparing the genotypes of individuals affected and not affected by primary open angle glaucoma juvenile onset (JOAG).
Ana Maria Marques, Galina Ananina, Vital Paulino Costa, José Paulo Cabral de Vasconcellos, Mônica Barbosa de Melo   +4 more
doaj   +1 more source

Evaluation of SPARC as a candidate gene of juvenile-onset primary open-angle glaucoma by mutation and copy number analyses. [PDF]

Mol Vis, 2010
Chen LJ, Tam PO, Tham CC, Liang XY, Chiang SW, Canlas O, Ritch R, Rhee DJ, Pang CP.   +8 more
europepmc   +1 more source

Keeping an Eye on Myocilin: A Complex Molecule Associated with Primary Open-Angle Glaucoma Susceptibility

Molecules, 2011
MYOC encodes a secretary glycoprotein of 504 amino acids named myocilin. MYOC is the first gene to be linked to juvenile open-angle glaucoma (JOAG) and some forms of adult-onset primary open-angle glaucoma (POAG).
Monica Barbosa De Melo, Eugênio Santana De Figueiredo, Bouzid Menaa, Vital Paulino Costa, Carolina Ayumi Braghini, Jose Paulo Cabral De Vasconcellos, Farid Menaa   +6 more
doaj   +1 more source

Glaucoma in Iran and contributions of studies in Iran to the understanding of the etiology of glaucoma

Journal of Ophthalmic & Vision Research, 2015
Epidemiologic and genetic/molecular research on glaucoma in Iran started within the past decade. A population-based study on the epidemiology of glaucoma in Yazd, a city in central Iran, revealed that 4.4% of studied individuals were affected with ...
Fatemeh Suri, Shahin Yazdani, Elahe Elahi   +2 more
doaj   +1 more source

Comparison between choroidal thickness in normal and glaucomatous eyes using spectral-domain optical coherence tomography

Delta Journal of Ophthalmology, 2017
Purpose The aim of this study was to compare choroidal thickness in healthy and glaucomatous eyes using spectral-domain optical coherence tomography. Patients and methods This prospective study was carried out on patients recruited from the Department ...
Mohsen A Abou Shousha, Karim M Nabil
doaj   +1 more source