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Assessment of Damage in Juvenile-Onset Systemic Lupus Erythematosus: A Multicenter Cohort Study. [PDF]

Arthritis and Rheumatism, 2003
AbstractObjectiveTo investigate the prevalence of cumulative organ damage in patients with juvenile‐onset systemic lupus erythematosus (SLE) and its association with demographic and clinical variables, medication use, and quality of life.MethodsThe occurrence of organ system damage, as measured by the Systemic Lupus International Collaborating Clinics ...
Alberto Martini, Nicolino Ruperto, Angelo Ravelli   +2 more
exaly   +4 more sources

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Anti‐C1q Antibodies in Juvenile‐Onset Systemic Lupus Erythematosus

Annals of the New York Academy of Sciences, 2009
The objective of this study was to evaluate the presence of anti‐C1q antibodies Hospital Israelita Albert Einstein Research Institute, São Paulo, Brazil in 67 juvenile systemic lupus erythematosus (JSLE) patients and 26 healthy controls and to assess the association of these antibodies with disease activity, nephritis, and presence of anti‐double ...
A A, Jesus, C A, Silva, M, Carneiro-Sampaio, M, Sheinberg, C L, Mangueira, S K, Marie, B L, Liphaus   +6 more
openaire   +2 more sources

Ocular Manifestations in Children with Juvenile-Onset Systemic Lupus Erythematosus

Seminars in Ophthalmology, 2017
To study the ocular manifestations of juvenile systemic lupus erythematosus (JSLE), including the ocular side-effects of the systemic medications used.A descriptive cross-sectional study on 40 children diagnosed with JSLE was conducted. Ophthalmological and laboratory investigations as well as a calculation of the Systemic Lupus Disease Activity Index ...
Ghada, Gawdat, Dina, El-Fayoumi, Huda, Marzouk, Yomna, Farag   +3 more
openaire   +2 more sources

THU0330 Damage in juvenile-onset systemic lupus erythematosus

Annals of the Rheumatic Diseases, 2012
Background Children and adolescents with juvenile-onset systemic lupus erythematosus (jSLE) face considerable morbidity due to sequelae of disease activity, comorbidities and adverse effects of treatment. In order to improve the management of these patients, it is essential to better understand the risk factors associated with the development of ...
P. Costa Reis, J. Isgro, S. Nativ, C. Yildirim-Toruner, A. Starr, L. Imundo, A. Eichenfield   +6 more
openaire   +1 more source

Analysis of serum IL-38 in juvenile-onset systemic lupus erythematosus

Modern Rheumatology, 2018
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with widespread immunologic abnormalities and multiple organ involvement [1].
Yusuke, Takeuchi, Tomoko, Seki, Norimoto, Kobayashi, Kenji, Sano, Tomonari, Shigemura, Hisashi, Shimojo, Kazuhiko, Matsumoto, Kazunaga, Agematsu   +7 more
openaire   +2 more sources

Multi-disciplinary care in juvenile-onset systemic lupus erythematosus

British Journal of School Nursing, 2012
Juvenile onset systemic lupus erythematosus (JSLE) is a chronic autoimmune disease that can affect any part of the body including skin, joints and organs and can be associated with significant morbidity and mortality. Multi-disciplinary care of children and young people with JSLE is essential, in close partnership with schools.
Jane Kelly, Jane Dunnage, Michael W Beresford, Liza J McCann   +3 more
openaire   +1 more source

Juvenile Onset Systemic Lupus Erythematosus Thyroid Dysfunction: A Subgroup With Mild Disease?

Journal of Autoimmunity, 2009
The aim of this study was to evaluate the frequency of thyroid dysfunction and thyroid antibodies in patients with juvenile onset Systemic Lupus Erythematosus (JOSLE) and its association with clinical and immunological features. Seventy-seven patients with JOSLE, 64 females, median age 19 years, were consecutively enrolled from March to December 2007 ...
Eloisa Silva Dutra de Olivera Bonfa, Rosa Maria Rodrigues Pereira   +1 more
exaly   +3 more sources

Juvenile-onset systemic lupus erythematosus: how to diagnose and manage

Paediatrics and Child Health, 2015
Abstract Systemic lupus erythematosus (SLE) is the prototypic autoimmune disorder, characterised by auto-antibody production against nuclear antigens. Juvenile-onset systemic lupus erythematosus (JSLE) is a more severe form than the adult-onset disease, with a more balanced gender ratio.
Louise Oni, Colin Thorbinson, Michael W. Beresford   +2 more
openaire   +1 more source

Herpes Zoster in Juvenile-Onset Systemic Lupus Erythematosus

The Pediatric Infectious Disease Journal, 2006
Herpes zoster (HZ) is common in systemic lupus erythematosus (SLE) patients, but its clinical features and risk factors in juvenile-onset SLE have not been well described before.A retrospective review of the clinical course and infections in pediatric SLE patients managed in our institution from 1988-2004 was performed.
HokKung Ho, M, Lau, YL, Lee, PPW, Lee, TL, Wong, WHS   +4 more
openaire   +5 more sources

HLA-DRB1 antigens in Taiwanese patients with juvenile-onset systemic lupus erythematosus

Rheumatology International, 2001
This study was done to investigate the frequency of HLA-DRB1 antigens in juvenile-onset systemic lupus erythematosus (SLE) in the Taiwanese population.Thirty-four Taiwanese patients with juvenile onset SLE and 200 unrelated healthy controls were studied.
J L, Huang, C K, Shaw, A, Lee, T D, Lee, Y H, Chou, M L, Kuo   +5 more
openaire   +2 more sources