Results 61 to 70 of about 1,112,704 (347)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

“EspaiJove.net”- a school-based intervention programme to promote mental health and eradicate stigma in the adolescent population: study protocol for a cluster randomised controlled trial

BMC Public Health, 2018
Background One half of adults who develop any mental disorder do so during adolescence. Previous literature showed that Mental Health Literacy (MHL) interventions impact mental health knowledge, reduce the associated stigma, and promote help-seeking ...
Rocío Casañas, Victoria-Mailen Arfuch, Pere Castellví, Juan-José Gil, Maria Torres, Angela Pujol, Gemma Castells, Mercè Teixidó, Maria Teresa San-Emeterio, Hernán María Sampietro, Aleix Caussa, Jordi Alonso, Lluís Lalucat-Jo   +12 more
doaj   +1 more source

Cell composition of blood for Salvelinus malma (Salmonidae) from the Raduga River (Kamchatka)

Известия ТИНРО, 2021
Hematopoiesis is a mechanism of multifunctional adaptation in vertebrates, including fish. Adaptive capabilities of populations are studied for a species of genus Salvelinus with high ecological plasticity.
O. E. Mazur, T. E. Boutorina, O. Yu. Busarova   +2 more
doaj   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Passive Avoidance Training and Recall are Associated With Increased Glutamate Levels in the Intermediate Medial Hyperstriatum Ventrale of the Day-Old Chick

Neural Plasticity, 1998
In the young chick, the intermediate medial hyperstriatum ventrale is involved in learning paradigms, including imprinting and passive avoidance learning. Biochemical changes in the intermediate medial hyperstriatum ventrale following learning include an
Jonathan N. Daisley, Michael Gruss, Steven P. R. Rose, Katharina Braun   +3 more
doaj   +1 more source

First Attack and Clinical Presentation of Hemiplegic Migraine in Pediatric Age: A Multicenter Retrospective Study and Literature Review

Frontiers in Neurology, 2019
Background: Data on clinical presentation of Hemiplegic Migraine (HM) are quite limited in the literature, particularly in the pediatric age. The aim of the present study is to describe in detail the phenotypic features at onset and during the first ...
Irene Toldo, Francesco Brunello, Veronica Morao, Egle Perissinotto, Massimiliano Valeriani, Dario Pruna, Elisabetta Tozzi, Filomena Moscano, Giovanni Farello, Roberto Frusciante, Marco Carotenuto, Carlo Lisotto, Silvia Ruffatti, Ferdinando Maggioni, Cristiano Termine, Gabriella Di Rosa, Margherita Nosadini, Stefano Sartori, Pier Antonio Battistella   +18 more
doaj   +1 more source

Feeding of arctic cod, walleye pollock, and other pelagic fish and their food supply in the Chukchi Sea in August-September, 2019

Известия ТИНРО, 2021
Data on feeding of fish are presented collected in the western Chukchi Sea aboard RV «Professor Levanidov» and in the eastern Chukchi Sea aboard RV «Ocean Starr» in August-September, 2019.
N. A. Kuznetsova, K. M. Gorbatenko
doaj   +1 more source

The Historical, Jurisprudential, and Empirical Wisdom of Parental Responsibility Laws [PDF]

, 2012
The parent-child relationship is woven deep within historical and contemporary culture, but strong retributive ideals have led to blaming parents because of their presumed vicarious role in juvenile crime.
Brank, Eve M., Scott, Leroy
core   +1 more source

Juvenile Dermatomyositis

Journal of Rheumatic Diseases, 2022
Juvenile dermatomyositis (JDM) is a systemic capillary vasculopathy. Patients present with proximal muscle weakness, raised muscle enzymes, and pathognomic skin rashes such as heliotrope rash, Gottron's papules. Main complications are calcinosis, lipodystrophy, osteoporosis. Complement-mediated damage of vessels is a major mechanism. Magnetic resonance
openaire   +3 more sources

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong, Shasha Yu, Jing Zhang, Yu Zu, Yujing Zhang, Jing Lv, Xuyang Cao, Xuedan Feng   +7 more
wiley   +1 more source