Results 51 to 60 of about 5,192,711 (150)
A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity [PDF]
Rheumatoid arthritis (RA) is a chronic inflammatory disease with a heritability of 60%. Genetic contributions to RA are made by multiple genes, but only a few gene associations have yet been confirmed.
Klareskog, Lars +25 more
core +1 more source
Pauciarticular juvenile arthritis associated with antinuclear factor and uveitis with onset at an early age has a special place in the structure of juvenile arthrites. This variant of arthritis is characterized by unpredictability of nosological outcomes
I. P. Nikishina +3 more
doaj +1 more source
Outcomes of Tocilizumab on the Disease Activity in Children with Juvenile Idiopathic Arthritis [PDF]
Background: Juvenile idiopathic arthritis (JIA) comprises a spectrum of chronic inflammatory joint disorders characterized by joint pain, swelling, stiffness, and restricted mobility in affected children. The interleukin-6 (IL-6) inhibitors, tocilizumab (
Rabab Elbehedy +5 more
doaj +1 more source
Results of research of anti-inflammatory action and complications of preparations ibuprofen, nimesulid, diclofenac sodium are submitted at treatment of children and the adolescent suffered from juvenile idiopathic arthritis during the sharp period of ...
V.A. Kel’tsev, L.I. Grebenkina
doaj +2 more sources
Background Physical activity (PA) patterns in children with juvenile idiopathic arthritis (JIA) over time are not well described. The aim of this study was to describe associations of physical activity (PA) with disease activity, function, pain, and ...
Liane D. Heale +35 more
doaj +1 more source
Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study [PDF]
Juvenile rheumatoid arthritis (JRA) comprises a group of chronic systemic inflammatory disorders that primarily affect joints and can cause long-term disability.
Woo, P +9 more
core
Background Some juvenile idiopathic arthritis (JIA) patients have a familial aggregation of the disease, and a few have been found to have a juvenile arthritis (JA) phenotype caused by a genetic mutation.
Yali Wu +4 more
doaj +1 more source
Leflunomide or methotrexate for juvenile rheumatoid arthritis.
BACKGROUND: We compared the safety and efficacy of leflunomide with that of methotrexate in the treatment of polyarticular juvenile rheumatoid arthritis in a multinational, randomized, controlled trial.
Lahdenne, P. +11 more
core +1 more source
Decreased high-density lipoprotein cholesterol levels in polyarticular juvenile idiopathic arthritis
OBJECTIVES: To investigate the prevalence of dyslipoproteinemia in a homogeneous cohort of polyarticular juvenile idiopathic arthritis patients. METHODS: Based on the National Cholesterol Education Program, fasting lipoprotein levels and risk levels for ...
Roberta Gonçalves Marangoni +5 more
doaj +1 more source
Background. Inflammatory bowel diseases, which include Crohn's disease and ulcerative colitis, are immune-mediated inflammatory diseases with a complex pathogenesis.
A. V. Polyanskaya +12 more
doaj +1 more source

