Juvenile idiopathic arthritis is common rheumatic disease in children and adolescents, but renal involvement is uncommon. Renal involvement is mostly in the form of secondary renal amyloidosis presenting as proteinuria.
Sudeep Patel +5 more
doaj +1 more source
THE ROLE OF APOPTOSIS VIOLATIONS IN THE JUVENILE IDIOPATHIC ARTHRITIS FORMATION
We investigated the polymorphism of the gene p53 exon 4 Arg72Pro and intron 3 ins/del 16 b. p. in children with juvenile idiopathic arthritis in order to identify the influence of gene polymorphisms on the course and outcome of the disease.
A. N. Kozhevnikov +4 more
doaj +1 more source
Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study. [PDF]
INTRODUCTION: Neovascularization contributes to the development of sustained synovial inflammation in the early stages of Rheumatoid Arthritis. Ultrasound (US) provides an indirect method of assessing synovial blood flow and has been shown to correlate ...
Kelly, S +23 more
core +1 more source
Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis [PDF]
Introduction Chemokines and their receptors control immune cell migration during infections as well as in autoimmune responses. A 32 bp deletion in the gene of the chemokine receptor CCR5 confers protection against HIV infection, but has also been ...
Rossol, Manuela +6 more
core +1 more source
Ovarian Reserve in Postpubertal Females with Juvenile Onset Idiopathic Arthritis [PDF]
Background: Juvenile onset idiopathic arthritis is a chronic inflammatory disease that predominantly affects females in their early reproductive years, rendering the importance of considering ovarian reserve and future fertility, which may still be ...
Sherif Kandeel +2 more
doaj +1 more source
Skin Manifestations of Rheumatoid Arthritis, Juvenile Idiopathic Arthritis, and Spondyloarthritides. [PDF]
Extra-articular manifestations of rheumatoid arthritis, juvenile idiopathic arthritis, and various spondyloarthritides including psoriatic arthritis, ankylosing spondylitis, reactive arthritis, and inflammatory bowel disease-associated spondyloarthritis ...
Nikhil Yawalkar +5 more
core +1 more source
Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY. [PDF]
The unparalleled collection of clinical data and biomaterials within the EHDN's REGISTRY can expedite the search for disease modifiers (genetic and environmental) of age at onset and disease progression that could be harnessed for the development of ...
Handley, Olivia J +59 more
core +1 more source
Systemic-onset juvenile idiopathic arthritis: the changing life of a rare disease
Systemic-onset juvenile idiopathic arthritis (SoJIA), sometimes called Still’s disease, is a systemic inflammatory disease classified within the spectrum of juvenile idiopathic arthritis (JIA).
Rolando Cimaz +2 more
doaj +1 more source
Cytokine status and hemostasis disorders in children with juvenile idiopathic arthritis
Juvenile idiopathic arthritis is a chronic inflammatory joint disease in children under 16 years of age associated with pathological immune response to various antigens. Probable factors are infectious and immunogenetic.
M. V. Gomellya +3 more
doaj +1 more source
The personal experience of parenting a child with Juvenile Huntington’s Disease: perceptions across Europe [PDF]
The study reported here presents a detailed description of what it is like to parent a child with juvenile Huntington’s disease in families across four European countries. Its primary aim was to develop and extend findings from a previous UK study.
Jonathan A Smith +29 more
core +1 more source

