JPGN Reports, EarlyView.Abstract Objective To determine if multiplex autoantibody arrays can identify novel biomarker signatures in children with one or multiple autoimmune diseases (polyautoimmunity). Methods Plasma collected from children (18 years or younger) in the Boston Children's Hospital Precision Link Biobank for Health Discovery between January 2007 and June 2021 ...
Nan Du +7 more
wiley +1 more source
Suppression of fever and the acute-phase response in a patient with juvenile chronic arthritis treated with monoclonal antibody to tumour necrosis factor-alpha (cA2) [PDF]
, 1997 Michael J. Elliott +5 more
openalex +1 more source
Obesity as a Risk Factor for Autoimmune Diseases: A Systematic Review and Meta‐Analysis
Obesity, EarlyView.Summary of the meta‐analysis including 26 studies (8 cross‐sectional, 18 longitudinal) investigating the association between obesity and autoimmune diseases. Findings show increased prevalence and incidence of rheumatoid arthritis, psoriasis, multiple sclerosis, and inflammatory bowel diseases in people with obesity, suggesting that obesity may ...
Ilaria Spatocco +12 more
wiley +1 more source
Spondylo-epiphyseal dysplasia tarda with progressive arthropathy mimicking juvenile chronic arthritis [PDF]
, 1998 PJ Byrne, K. T. Rajan
openalex +1 more source
IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak +7 more
wiley +1 more source
Decreased fibrinolytic activity in juvenile chronic arthritis. [PDF]
, 1990 L. Mussoni +5 more
openalex +1 more source
Tubulointerstitial nephritis and uveitis syndrome in children: What to keep an eye on
Acta Ophthalmologica, EarlyView.Abstract Purpose The purpose of this study was to determine the disease course in patients with tubulointerstitial nephritis and uveitis (TINU) syndrome, focusing on long‐term outcome and the incidence of complications such as chronic kidney disease (CKD).
Jytte Hendrikse +4 more
wiley +1 more source
Previous synovectomy or epiphyseal stapling and the influence on knee replacement in juvenile chronic arthritis [PDF]
, 2004 C. O. Lyb�ck +5 more
openalex +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Absence of association between interleukin 1 alpha and oligoarticular juvenile chronic arthritis in UK patients [PDF]
, 1999 Rachelle Donn
openalex +1 more source