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Immunopathogenesis of juvenile dermatomyositis
Muscle & Nerve, 2010AbstractThere is increasing evidence for involvement of the mechanisms of the innate immune system in the pathogenesis of idiopathic inflammatory myopathies (IIMs), especially in the adult and juvenile forms of dermatomyositis. Juvenile dermatomyositis (JDM) is the most common form of childhood IIM, and this review focuses on recent advances in ...
Sahil, Khanna, Ann M, Reed
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Panniculitis in Juvenile Dermatomyositis
Pediatric Dermatology, 1999Abstract: Panniculitis is a rarely reported clinical finding in dermatomyositis. We present a 14‐year‐old African American boy with a 4‐year history of dermatomyositis referred for evaluation of tender, indurated plaques and nodules on the trunk and proximal extremities.
F E, Ghali +3 more
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Neutrophil Extracellular Traps in Tissue and Periphery in Juvenile Dermatomyositis
Arthritis & Rheumatology, 2020Neutrophils are key immune cells participating in host defense through several mechanisms, including the formation of neutrophil extracellular traps (NETs). This study was undertaken to investigate the role of neutrophils in juvenile dermatomyositis (JDM)
Bhargavi Duvvuri +7 more
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HIV with Juvenile Dermatomyositis
The Indian Journal of Pediatrics, 2013Dermatomyositis with HIV infection has been very rarely reported. The authors report an 8-y-old boy who presented with skin rashes and edema, muscle weakness and polymicrobial infection along with mild immunosupression. Diagnosis of dermatomyositis was established by raised enzymes, suggestive MRI and muscle biopsy findings. Child responded to systemic
Varun Kumar, Sharma +4 more
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An update on juvenile dermatomyositis
Current Opinion in Rheumatology, 1995Juvenile dermatomyositis (JDMS) is a systemic vasculopathy characterized primarily by inflammation of skin and muscle. JDMS is identified in more than three per million persons per year, using established diagnostic criteria. Although originally thought to be a relatively homogeneous disease, new data confirm that heterogeneity in JDMS may be found at ...
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Calcinosis in Juvenile Dermatomyositis
New England Journal of Medicine, 2019Calcinosis in Juvenile Dermatomyositis A 4-year-old girl with juvenile dermatomyositis presented with weakness, rash, and palpable subcutaneous nodules.
Jianguo, Li, Zhixuan, Zhou
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Erythrodermic Juvenile Dermatomyositis
Pediatric Dermatology, 2009Abstract: Juvenile dermatomyositis (JDMS) is an inflammatory myopathy with various cutaneous manifestations, usually affecting children between 2 and 15 years of age. We describe a 9‐year‐old female diagnosed with Juvenile dermatomyositis presenting with generalized erythroderma, Gottron papules, inflammatory myopathy associated with systemic ...
Ram, Chander +3 more
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Actuality of juvenile dermatomyositis
Joint Bone Spine, 2011Juvenile dermatomyositis is a rare disorder, but remains the most commonly occurring chronic inflammatory myopathy among children. Other than the proximal muscles and skin, which are routinely affected, vasculopathy may affect other viscera and can be multisystemic.
Amine, Zouagui +7 more
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An update on juvenile dermatomyositis.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2014Juvenile dermatomyositis (JDM) is a rare, severe, autoimmune disease characterized by a small-vessel vasculopathy that primarily affects skin and muscle, but also lung, joints, gut and heart. Nowadays prompt recognition of this entity and aggressive treatment, when needed, improves outcomes and has decreased mortality that, before corticosteroid became
Boccaletti V +4 more
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