Results 91 to 100 of about 1,174 (215)

Disruption of reproductive and thyroid endocrine systems in zebrafish following early life and whole life cycle exposure to low-dose norgestrel

Ecotoxicology and Environmental Safety
Norgestrel (NGT), a synthetic progestin, is frequently detected in aquatic environments and known to disrupt fish endocrine systems. In this study, zebrafish embryos were exposed to low NGT concentrations (9 and 66 ng/L) for 90 days post-fertilization ...
Shuyan Mai, Weicai Hu, Yan-Qiu Liang, Zhongdian Dong, Chang-Gui Pan, Zhiyun Liu, Runting Ouyang, Yangjie Zeng, Zhong Lin, Liping Hou   +9 more
doaj   +1 more source

The Natural History of Residual and Recurrent Disease in Advanced Juvenile Nasopharyngeal Angiofibroma: A Systematic Review

The Laryngoscope, EarlyView.
Residual and recurrent disease in advanced juvenile nasopharyngeal angiofibromas (JNAs) demonstrate spontaneous involution, reduction in size, or long‐term stability following initial treatment in 95% of patients. In this systematic review of 131 patients with advanced JNA, only 2% of patients demonstrated disease progression during surveillance, but ...
Shivani Angelique Kumar, Peter Petocz, Raewyn G. Campbell   +2 more
wiley   +1 more source

The seminal vesicle is a juvenile hormone-responsive tissue in adult male Drosophila melanogaster

Open Biology
Juvenile hormone (JH) is one of the most essential hormones controlling insect metamorphosis and physiology. While it is well known that JH affects many tissues throughout the insect life cycle, the difference in JH responsiveness and the repertoire of ...
Yoshitomo Kurogi, Yosuke Mizuno, Ryosuke Hayashi, Krystal Goyins, Naoki Okamoto, Lacy Barton, Ryusuke Niwa   +6 more
doaj   +1 more source

Endoscopic small bowel therapies for type 2 diabetes

Nutrition in Clinical Practice, EarlyView.
Abstract Type 2 diabetes is a global epidemic despite current medical treatments. Many patients are not responsive to medications, and patients with obesity are hesitant about bariatric surgery. Studies investigating the metabolic effects of Roux‐en‐Y gastric bypass have increasingly demonstrated that the duodenum plays a key role in the ...
Roma Patel, Zehra Naseem, Prisha Gattu, Stephen Firkins, Roberto Simons‐Linares   +4 more
wiley   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

Obesity, EarlyView.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter, Julie Mount, J. Martin Gibson, Joanne Webb, Cheryl Marler, Catherine Reed, Mugdha Gore, Wenyu Ye, Elisa Gomez Valderas, John Wilding, Naveed Sattar, Melanie J. Davies, Kamlesh Khunti, Richard Haynes, Rachel L. Batterham   +14 more
wiley   +1 more source

Validation of a novel bioassay method for the evaluation of the activity of slow‐acting insecticides on tomato borer Phthorimaea absoluta

Pest Management Science, EarlyView.
Extended bioassays revealed that azadirachtin and spirotetramat show strong delayed effects against Phthorimaea absoluta, underestimated by the standard Insecticide Resistance Action Committee (IRAC) method 022 protocol. Incorporating long‐term exposures is essential to accurately assess slow‐acting insecticides and improve resistance management ...
Marianna Stavrakaki, Kyriaki Mylona, Dimitris Piperidis, George Afantenos, Katerina Kremi, Konstantina Alipranti, Konstantinos B. Simoglou, Emmanouil Roditakis   +7 more
wiley   +1 more source

Effects of the use of growth hormone in children and adolescents with juvenile idiopathic arthritis: a systematic review

Revista Brasileira de Reumatologia
Introduction: Children with juvenile idiopathic arthritis (JIA) often have impaired growth and short stature. There is evidence that the therapeutic use of growth hormone (GH) is useful and safe in these patients. Objective: To analyze the effects of GH
Renan Bazuco Frittoli, Barbara Sugui Longui, Amanda Meireles Silva, Antônio de Azevedo Barros Filho, Maria Ângela Reis de Góes Monteiro, Simone Appenzeller   +5 more
doaj   +1 more source

Long‐term impact of exposure to Royal Guard, a pyriproxyfen‐based bed net, on pyrethroid‐resistant malaria vectors from Cameroon using DNA‐based metabolic resistance markers

Pest Management Science, Volume 81, Issue 4, Page 2165-2180, April 2025.
We used recently detected P450 DNA‐based markers of pyrethroid resistance in both Anopheles funestus and Anopheles gambiae to demonstrate that although pyrethroid‐resistant mosquitoes have higher ability to survive and live longer after exposure to Royal Guard, this net significantly affects their lifespan, blood feeding ability and interestingly ...
Emilie S Ngongang‐Yipmo, Magellan Tchouakui, Benjamin D Menze, Riccado F Tiomela, Derrick Fofie, Vanessa B Ngannang‐Fezeu, Jean L Mugenzi, Flobert Njiokou, Charles S Wondji   +8 more
wiley   +1 more source

Type I interferon overactivation in sera of patients with anti‐MDA5‐positive dermatomyositis‐associated interstitial lung disease

Rheumatology &Autoimmunity, EarlyView.
Sera from patients with anti‐MDA5‐positive dermatomyositis‐associated interstitial lung disease (ILD) exhibit significantly higher type I interferon (IFN‐I) bioactivity and interferon‐stimulated gene‐inducing activity compared to anti‐ARS‐positive ILD and healthy controls.
Shohei Nakamura, Yasuhiro Katsumata, Yuko Okamoto, Masayoshi Harigai   +3 more
wiley   +1 more source

An Outline of a Theory of Play

Symbolic Interaction, EarlyView.
Play is often dismissed as trivial, yet it is a fundamental and adaptive aspect of human and mammalian life. This paper develops a sociological theory of play, treating it as a total social fact that spans biological, psychological, and social dimensions.
Seth Abrutyn
wiley   +1 more source