Ecdysone coordinates plastic growth with robust pattern in the developing wing
eLife, 2022 Animals develop in unpredictable, variable environments. In response to environmental change, some aspects of development adjust to generate plastic phenotypes.
André Nogueira Alves +4 more
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Ecdysone signaling acts as a regulator of immunity and microbiota balance, shaping Leishmania infantum infection in Phlebotomus perniciosus [PDF]
Frontiers in ImmunologyBackgroundThe steroid hormone ecdysone, acting through its nuclear receptor (EcR), is a key regulator of insect development and reproduction and also contributes to immune regulation and gut microbiota homeostasis.
Cecilia Stahl Vieira +4 more
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Ecdysone Quantification from Whole Body Samples of Drosophila melanogaster Larvae
Bio-Protocol, 2021 Steroid hormones strictly control the timing of sexual maturation and final body size both in vertebrates and invertebrates. In insects, the steroid hormone ecdysone controls the timing of the molts between larval instars as well as the transition to ...
Takashi Koyama, Christen Mirth
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The insulin and ecdysone pathways as regulators of diapause termination: transcriptional and protein insights from Pieris napi [PDF]
BMC GenomicsInsect diapause is a pre-programmed alternative developmental pathway induced to survive adverse environmental conditions and is characterized by an absence of development, metabolic suppression and increased stress resistance.
Philip Süess +6 more
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Nup107 is a crucial regulator of torso-mediated metamorphic transition in Drosophila melanogaster [PDF]
eLifeNuclear pore complexes (NPCs), composed of nucleoporins (Nups), affect nucleocytoplasmic transport, thus influencing cell division and gene regulation.
Jyotsna Kawadkar +2 more
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Larval diapause termination in the bamboo borer, Omphisa fuscidentalis. [PDF]
PLoS ONE, 2017 In insects, juvenile hormone (JH) and 20-hydroxyecdysone (20E) regulate larval growth and molting. However, little is known about how this cooperative control is terminating larval diapause especially in the bamboo borer, Omphisa fuscidentalis.
Suphawan Suang +7 more
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Nuclear receptor DHR4 controls the timing of steroid hormone pulses during Drosophila development. [PDF]
PLoS Biology, 2011 In insects, precisely timed periodic pulses of the molting hormone ecdysone control major developmental transitions such as molts and metamorphosis. The synthesis and release of ecdysone, a steroid hormone, is itself controlled by PTTH (prothoracicotopic
Qiuxiang Ou +2 more
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Open Chemistry, 2022 β-Ecdysone is a phytosteroid derived from multifarious medicinal plants, such as Achyranthes root (Achyranthes bidentata) and Tinospora cordifolia, possessing the potential anti-osteoporosis effect.
Zeng Bin +3 more
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Identification of Ecdysone Hormone Receptor Agonists as a Therapeutic Approach for Treating Filarial Infections. [PDF]
PLoS Neglected Tropical Diseases, 2016 BACKGROUND:A homologue of the ecdysone receptor has previously been identified in human filarial parasites. As the ecdysone receptor is not found in vertebrates, it and the regulatory pathways it controls represent attractive potential chemotherapeutic ...
Amruta S Mhashilkar +8 more
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Ecdysone acts through cortex glia to regulate sleep in Drosophila
eLife, 2023 Steroid hormones are attractive candidates for transmitting long-range signals to affect behavior. These lipid-soluble molecules derived from dietary cholesterol easily penetrate the brain and act through nuclear hormone receptors (NHRs) that function as
Yongjun Li +4 more
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