Ecdysone Elicits Chronic Renal Impairment via Mineralocorticoid-Like Pathogenic Activities [PDF]
Cellular Physiology and Biochemistry, 2018 Background/Aims: Ecdysteroids are steroidal insect molting hormones that also exist in herbs. Ecdysteroid-containing adaptogens have been popularly used to improve well-being and by bodybuilders for muscle growth.
Minglei Lu +9 more
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Mechanisms of transcriptional regulation of ecdysone response [PDF]
Вавиловский журнал генетики и селекции, 2019 The mechanisms of ecdysone-dependent expression have been studied for many decades. Initially, the activation of individual genes under the influence of ecdysone was studied on the model of polythene chromosomes from salivary glands of Drosophila ...
M. Yu. Mazina, N. E. Vorobyeva
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A Genetic Mosaic Screen Reveals Ecdysone-Responsive Genes Regulating Drosophila Oogenesis
G3: Genes, Genomes, Genetics, 2016 Multiple aspects of Drosophila oogenesis, including germline stem cell activity, germ cell differentiation, and follicle survival, are regulated by the steroid hormone ecdysone.
Elizabeth T. Ables +4 more
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The steroid-hormone ecdysone coordinates parallel pupariation neuromotor and morphogenetic subprograms via epidermis-to-neuron Dilp8-Lgr3 signal induction [PDF]
Nature Communications, 2021 Pupariation in Drosophila is triggered by the steroid-hormone ecdysone and requires coordination between associated behavioral and body-reshaping motor subprograms.
Fabiana Heredia +19 more
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Azadirachtin disrupts ecdysone signaling and alters sand fly immunity [PDF]
Parasites & VectorsBackground Leishmaniasis is a group of neglected vector-borne diseases transmitted by phlebotomine sand flies. Leishmania parasites must overcome various defenses in the sand fly midgut, including the insects’s immune response.
Cecilia Stahl Vieira +4 more
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A Drosophila ecdysone-deficient model to assess the endocrine disruptor activity of Bisphenol A
Ecotoxicology and Environmental SafetyBisphenol A (BPA) is a well characterized endocrine disruptor that interferes with the activity of a variety of nuclear receptors. For this reason, BPA has the potential to impact the function of the endocrine system and alter cellular physiology.
Patricia Vega-Cuesta +8 more
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A Tale of Two States: Similarities and Differences in Neuropeptide Signaling in Larval and Adult Drosophila. [PDF]
J Comp NeurolNeurosecretory cells of the brain are mostly the same in larvae and adults of Drosophila melanogaster and they produce the same neuropeptides and peptide hormones (NPHs), yet their functional roles differ to a large extent between the two stages. Many other peptidergic neurons change both in numbers and function.
Nässel DR.
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Essential functions of mosquito ecdysone importers in development and reproduction [PDF]
, 2022 The primary insect steroid hormone ecdysone requires a membrane transporter to enter its target cells. Although an organic anion-transporting polypeptide (OATP) named Ecdysone Importer (EcI) serves this role in the fruit fly Drosophila melanogaster and ...
Bittar, Riyan +12 more
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PLoS Genetics, 2021 Insect metamorphosis is triggered by the production, secretion and degradation of 20-hydroxyecdysone (ecdysone). In addition to its role in developmental regulation, increasing evidence suggests that ecdysone is involved in innate immunity processes ...
Catarina Nunes +2 more
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Coregulators Reside within Drosophila Ecdysone-Inducible Loci before and after Ecdysone Treatment
, 2023 Ecdysone signaling in Drosophila remains a popular model for investigating the mechanisms of steroid action in eukaryotes. The ecdysone receptor EcR can effectively bind ecdysone-response elements with or without the presence of a hormone. For years, EcR
Maksim Erokhin +5 more
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