Pigment dispersing factor regulates ecdysone biosynthesis via bombyx neuropeptide G protein coupled receptor-B2 in the prothoracic glands of Bombyx mori. [PDF]
PLoS ONE, 2014 Ecdysone is the key hormone regulating insect growth and development. Ecdysone synthesis occurs in the prothoracic glands (PGs) and is regulated by several neuropeptides.
Masatoshi Iga +3 more
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Coregulators Reside within Drosophila Ecdysone-Inducible Loci before and after Ecdysone Treatment
, 2023 Ecdysone signaling in Drosophila remains a popular model for investigating the mechanisms of steroid action in eukaryotes. The ecdysone receptor EcR can effectively bind ecdysone-response elements with or without the presence of a hormone. For years, EcR
Maksim Erokhin +5 more
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Novel roles for ecdysone receptor in the Drosophila germline
, 2023 Oogenesis, the process by which a viable egg is produced, demands carefully coordinated communication between somatic and germ cell populations, relying on both local and systemic factors such as steroid hormones for signaling. In Drosophila, the steroid
NC DOCKS at East Carolina University +1 more
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Steroid hormone control of cell death and cell survival: molecular insights using RNAi.
PLoS Genetics, 2009 The insect steroid hormone ecdysone triggers programmed cell death of obsolete larval tissues during metamorphosis and provides a model system for understanding steroid hormone control of cell death and cell survival.
Suganthi Chittaranjan +5 more
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Molecular evidence for a functional ecdysone signaling system in Brugia malayi. [PDF]
PLoS Neglected Tropical Diseases, 2010 BACKGROUND:Filarial nematodes, including Brugia malayi, the causative agent of lymphatic filariasis, undergo molting in both arthropod and mammalian hosts to complete their life cycles.
George Tzertzinis +7 more
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Molecular characterisation of the salmon louse, Lepeophtheirus salmonis salmonis (Krøyer, 1837), ecdysone receptor with emphasis on functional studies of female reproduction [PDF]
, 2014 The salmon louse Lepeophtheirus salmonis (Copepoda, Caligidae) is an important parasite in the salmon farming industry in the Northern Hemisphere causing annual losses of hundreds of millions of dollars (US) worldwide.
Grotmol, Sindre +6 more
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Bab2 Functions as an Ecdysone-Responsive Transcriptional Repressor during Drosophila Development
Cell Reports, 2020 Summary: Drosophila development is governed by distinct ecdysone steroid pulses that initiate spatially and temporally defined gene expression programs. The translation of these signals into tissue-specific responses is crucial for metamorphosis, but the
Jianli Duan +7 more
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Increased insulin/insulin growth factor signaling advances the onset of metamorphosis in Drosophila. [PDF]
PLoS ONE, 2009 Mechanisms by which attainment of specific body sizes trigger developmental transitions to adulthood (e.g. puberty or metamorphosis) are incompletely understood.
Magdalena A Walkiewicz, Michael Stern
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The ecdysone receptor puzzle [PDF]
, 1999 : The present article reviews some recent findings on the functional ecdysone † receptor which is a heterodimer of two proteins: ecdysone receptor (EcR) and Ultraspiracle (USP).
T Bergman +5 more
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Nature Communications, 2017 InDrosophila, ecdysone-regulated genes are bound by a heterodimer of ecdysone receptor (EcR) and Ultraspiracle. Here, the authors provide evidence of a non-canonical complex containing EcR and the nucleosome remodeller dMi-2 that limits transcription of ...
Judith Kreher +10 more
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