Results 31 to 40 of about 8,028 (164)

N(alpha)-acetyltransferase 40-mediated histone acetylation plays an important role in ecdysone regulation of metamorphosis in the red flour beetle, Tribolium castaneum

Communications Biology
Histone acetylation, a crucial epigenetic modification, is governed by histone acetyltransferases (HATs), that regulate many biological processes. Functions of HATs in insects are not well understood.
Sharath Chandra Gaddelapati, Smitha George, Anilkumar Moola, Karthi Sengodan, Subba Reddy Palli   +4 more
doaj   +1 more source

Translational control by the DEAD Box RNA helicase belle regulates ecdysone-triggered transcriptional cascades.

PLoS Genetics, 2012
Steroid hormones act, through their respective nuclear receptors, to regulate target gene expression. Despite their critical role in development, physiology, and disease, however, it is still unclear how these systemic cues are refined into tissue ...
Robert J Ihry, Anne L Sapiro, Arash Bashirullah   +2 more
doaj   +1 more source

Pri smORF Peptides Are Wide Mediators of Ecdysone Signaling, Contributing to Shape Spatiotemporal Responses

Frontiers in Genetics, 2021
There is growing evidence that peptides encoded by small open-reading frames (sORF or smORF) can fulfill various cellular functions and define a novel class regulatory molecules.
Azza Dib, Jennifer Zanet, Alexandra Mancheno-Ferris, Maylis Gallois, Damien Markus, Philippe Valenti, Simon Marques-Prieto, Serge Plaza, Yuji Kageyama, Yuji Kageyama, Hélène Chanut-Delalande, François Payre   +11 more
doaj   +1 more source

The insulator protein CTCF regulates Drosophila steroidogenesis

Biology Open, 2015
The steroid hormone ecdysone is a central regulator of insect development. In this report we show that CTCF expression in the prothoracic gland is required for full transcriptional activation of the Halloween genes spookier, shadow and noppera-bo, which ...
Ujué Fresán, Sergi Cuartero, Michael B. O'Connor, M. Lluisa Espinàs   +3 more
doaj   +1 more source

Impact of steroid hormone signals on Drosophila cell cycle during development

Cell Division, 2009
Metamorphosis of Drosophila involves proliferation, differentiation and death of larval tissues in order to form the adult fly. The major steroid hormone implicated in the larval-pupal transition and adult tissue modelling is ecdysone.
Quinn Leonie, Cranna Nicola
doaj   +1 more source

Azadirachtin disrupts ecdysone signaling and alters sand fly immunity

Parasites & Vectors
Background Leishmaniasis is a group of neglected vector-borne diseases transmitted by phlebotomine sand flies. Leishmania parasites must overcome various defenses in the sand fly midgut, including the insects’s immune response.
Cecilia Stahl Vieira, Sara Bisogno, Marco Salvemini, Erich Loza Telleria, Petr Volf   +4 more
doaj   +1 more source

Unexpected role of the steroid-deficiency protein ecdysoneless in pre-mRNA splicing. [PDF]

PLoS Genetics, 2014
The steroid hormone ecdysone coordinates insect growth and development, directing the major postembryonic transition of forms, metamorphosis. The steroid-deficient ecdysoneless1 (ecd1) strain of Drosophila melanogaster has long served to assess the ...
Ann-Katrin Claudius, Patrizia Romani, Tobias Lamkemeyer, Marek Jindra, Mirka Uhlirova   +4 more
doaj   +1 more source

Role of Broad-Complex (Br) and Krüppel homolog 1 (Kr-h1) in the Ovary Development of Nilaparvata lugens

Frontiers in Physiology, 2017
Ovarian development plays an important role in the life history of insects and is crucial for control of the insect population. The metamorphosis of an insect is precisely regulated by the interaction of the juvenile hormone and ecdysone.
Jianru Jiang, Yili Xu, Xinda Lin
doaj   +1 more source

Extracellular matrix induced by steroids and aging through a G-protein-coupled receptor in a Drosophila model of renal fibrosis

Disease Models & Mechanisms, 2020
Aldosterone is produced by the mammalian adrenal cortex to modulate blood pressure and fluid balance; however, excessive, prolonged aldosterone promotes fibrosis and kidney failure.
Wenjing Zheng, Karen Ocorr, Marc Tatar
doaj   +1 more source

Ecdysone Oxidase: Reaction and Specificity [PDF]

European Journal of Biochemistry, 1978
Ecdysone oxidase oxidizes 3‐hydroxysteroids of the ecdysteroid type irreversibly to 3‐dehydro derivatives. The hydrogen of the steroid is transferred by the enzyme to oxygen which is reduced to hydrogen peroxide. Ecdysone oxidase is relatively specific for ecdysone and ecdysterone. Apparent Michaelis constants for these two physiological substrates are
J, Koolman, P, Karlson
openaire   +2 more sources