Results 21 to 30 of about 10,510 (219)
Nuclear receptor DHR4 controls the timing of steroid hormone pulses during Drosophila development. [PDF]
PLoS Biology, 2011 In insects, precisely timed periodic pulses of the molting hormone ecdysone control major developmental transitions such as molts and metamorphosis. The synthesis and release of ecdysone, a steroid hormone, is itself controlled by PTTH (prothoracicotopic
Qiuxiang Ou +2 more
doaj +1 more source
Open Chemistry, 2022 β-Ecdysone is a phytosteroid derived from multifarious medicinal plants, such as Achyranthes root (Achyranthes bidentata) and Tinospora cordifolia, possessing the potential anti-osteoporosis effect.
Zeng Bin +3 more
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Essential functions of mosquito ecdysone importers in development and reproduction [PDF]
, 2022 The primary insect steroid hormone ecdysone requires a membrane transporter to enter its target cells. Although an organic anion-transporting polypeptide (OATP) named Ecdysone Importer (EcI) serves this role in the fruit fly Drosophila melanogaster and ...
Bittar, Riyan +6 more
core +1 more source
Identification of Ecdysone Hormone Receptor Agonists as a Therapeutic Approach for Treating Filarial Infections. [PDF]
PLoS Neglected Tropical Diseases, 2016 BACKGROUND:A homologue of the ecdysone receptor has previously been identified in human filarial parasites. As the ecdysone receptor is not found in vertebrates, it and the regulatory pathways it controls represent attractive potential chemotherapeutic ...
Amruta S Mhashilkar +8 more
doaj +1 more source
Heterokairic Genes and the Eco‐Evo‐Devo of Timing [PDF]
Evol DevHeterokairic genes as the bridge (Heterokairic Pathways?): Heterokairic genes are heterochronic regulators whose activity is modulated by environmental conditions. External cues (e.g., temperature, nutrition, oxygen, density: yellow box) are sensed (yellow arrows) and converted into endocrine and metabolic signals (purple box and arrow into fish's ...
Lofeu L, Ahi E.
europepmc +2 more sources
Ecdysone acts through cortex glia to regulate sleep in Drosophila
eLife, 2023 Steroid hormones are attractive candidates for transmitting long-range signals to affect behavior. These lipid-soluble molecules derived from dietary cholesterol easily penetrate the brain and act through nuclear hormone receptors (NHRs) that function as
Yongjun Li +4 more
doaj +1 more source
PLoS Genetics, 2021 Insect metamorphosis is triggered by the production, secretion and degradation of 20-hydroxyecdysone (ecdysone). In addition to its role in developmental regulation, increasing evidence suggests that ecdysone is involved in innate immunity processes ...
Catarina Nunes +2 more
doaj +1 more source
Insects, 2022 In the present study, we observed a 58% decrease in the fecundity of Drosophila melanogaster, after treatment with the cyromazine. To further elucidate the effects of cyromazine on reproduction, we counted the number of both germline stem cells (GSCs ...
Muhammad Zaryab Khalid +4 more
doaj +1 more source
Spider Hemocyanin Binds Ecdysone and 20-OH-Ecdysone [PDF]
Journal of Biological Chemistry, 1999 Fluorescence quenching studies and binding experiments with [(3)H]ecdysone reveal that the respiratory protein, hemocyanin, of the tarantula Eurypelma californicum binds ecdysone. The binding constant for ecdysone ranges between 0.5 and 5 mM, indicating a low affinity binding.
E, Jaenicke, R, Föll, H, Decker
openaire +2 more sources
The ecdysone receptor regulates several key physiological factors in Anopheles funestus
Malaria Journal, 2022 Background Malaria is a devastating disease, transmitted by female Anopheles mosquitoes infected with Plasmodium parasites. Current insecticide-based strategies exist to control the spread of malaria by targeting vectors.
Surina Maharaj +6 more
doaj +1 more source