Results 21 to 30 of about 23,839 (265)

Heterokairic Genes and the Eco‐Evo‐Devo of Timing [PDF]

open access: yesEvol Dev
Heterokairic genes as the bridge (Heterokairic Pathways?): Heterokairic genes are heterochronic regulators whose activity is modulated by environmental conditions. External cues (e.g., temperature, nutrition, oxygen, density: yellow box) are sensed (yellow arrows) and converted into endocrine and metabolic signals (purple box and arrow into fish's ...
Lofeu L, Ahi E.
europepmc   +2 more sources

Essential functions of mosquito ecdysone importers in development and reproduction

open access: yesbioRxiv, 2021
The primary insect steroid hormone ecdysone requires a membrane transporter to enter its target cells. Although an organic anion-transporting polypeptide (OATP) named Ecdysone Importer (EcI) serves this role in the fruit fly Drosophila melanogaster and ...
Lewis V. Hun   +5 more
semanticscholar   +1 more source

Network pharmacology combined with molecular docking to explore the anti-osteoporosis mechanisms of β-ecdysone derived from medicinal plants

open access: yesOpen Chemistry, 2022
β-Ecdysone is a phytosteroid derived from multifarious medicinal plants, such as Achyranthes root (Achyranthes bidentata) and Tinospora cordifolia, possessing the potential anti-osteoporosis effect.
Zeng Bin   +3 more
doaj   +1 more source

Mapping molluscan endocrinology: a systematic and critical appraisal. [PDF]

open access: yesBiol Rev Camb Philos Soc
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Panagiotidis K   +3 more
europepmc   +2 more sources

Nuclear receptor DHR4 controls the timing of steroid hormone pulses during Drosophila development. [PDF]

open access: yesPLoS Biology, 2011
In insects, precisely timed periodic pulses of the molting hormone ecdysone control major developmental transitions such as molts and metamorphosis. The synthesis and release of ecdysone, a steroid hormone, is itself controlled by PTTH (prothoracicotopic
Qiuxiang Ou   +2 more
doaj   +1 more source

Ecdysone steroid hormone remote controls intestinal stem cell fate decisions via the PPARγ-homolog Eip75B in Drosophila

open access: yesbioRxiv, 2020
Developmental studies revealed fundamental principles on how organ size and function is achieved, but less is known about organ adaptation to new physiological demands.
Lisa Zipper   +4 more
semanticscholar   +1 more source

Ecdysone acts through cortex glia to regulate sleep in Drosophila

open access: yeseLife, 2023
Steroid hormones are attractive candidates for transmitting long-range signals to affect behavior. These lipid-soluble molecules derived from dietary cholesterol easily penetrate the brain and act through nuclear hormone receptors (NHRs) that function as
Yongjun Li   +4 more
doaj   +1 more source

Egfr Signaling Is a Major Regulator of Ecdysone Biosynthesis in the Drosophila Prothoracic Gland.

open access: yesCurrent Biology, 2020
Understanding the mechanisms that determine final body size of animals is a central question in biology. In animals with determinate growth, such as mammals or insects, the size at which the immature organism transforms into the adult defines the final ...
Josefa Cruz   +2 more
semanticscholar   +1 more source

Co-option of immune effectors by the hormonal signalling system triggering metamorphosis in Drosophila melanogaster.

open access: yesPLoS Genetics, 2021
Insect metamorphosis is triggered by the production, secretion and degradation of 20-hydroxyecdysone (ecdysone). In addition to its role in developmental regulation, increasing evidence suggests that ecdysone is involved in innate immunity processes ...
Catarina Nunes   +2 more
doaj   +1 more source

Resource Availability Modulates Gene Expression Across Life Stages in a Migratory Butterfly. [PDF]

open access: yesMol Ecol
ABSTRACT Natural populations are in constant need of balancing resource allocation to compensate for seasonal environmental variation. In many insects, a well‐established trade‐off between migration and reproduction exists. While this trade‐off has been characterised phenotypically for decades, the underlying regulatory pathways are poorly understood ...
Shipilina D   +8 more
europepmc   +2 more sources

Home - About - Disclaimer - Privacy