Results 21 to 30 of about 8,028 (164)
Increased insulin/insulin growth factor signaling advances the onset of metamorphosis in Drosophila. [PDF]
PLoS ONE, 2009 Mechanisms by which attainment of specific body sizes trigger developmental transitions to adulthood (e.g. puberty or metamorphosis) are incompletely understood.
Magdalena A Walkiewicz, Michael Stern
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Nutritional control of body size through FoxO-Ultraspiracle mediated ecdysone biosynthesis
eLife, 2014 Despite their fundamental importance for body size regulation, the mechanisms that stop growth are poorly understood. In Drosophila melanogaster, growth ceases in response to a peak of the molting hormone ecdysone that coincides with a nutrition ...
Takashi Koyama +4 more
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Nature Communications, 2017 InDrosophila, ecdysone-regulated genes are bound by a heterodimer of ecdysone receptor (EcR) and Ultraspiracle. Here, the authors provide evidence of a non-canonical complex containing EcR and the nucleosome remodeller dMi-2 that limits transcription of ...
Judith Kreher +10 more
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Memorias do Instituto Oswaldo Cruz, 1988 Third instar larvae of Stomoxys calcitrans (L.) were treated with precocene II, ecdysone and juvenile hormone. The larvae were allowed to develop until pupation and when it occurred, determination of glycogen levels was assayed.
M. L. M. Garcia +2 more
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Coordinated regulation of niche and stem cell precursors by hormonal signaling. [PDF]
PLoS Biology, 2011 Stem cells and their niches constitute units that act cooperatively to achieve adult body homeostasis. How such units form and whether stem cell and niche precursors might be coordinated already during organogenesis are unknown.
Dana Gancz, Tamar Lengil, Lilach Gilboa
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Nature Communications, 2021 Pupariation in Drosophila is triggered by the steroid-hormone ecdysone and requires coordination between associated behavioral and body-reshaping motor subprograms.
Fabiana Heredia +19 more
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Deep sequencing of the prothoracic gland transcriptome reveals new players in insect ecdysteroidogenesis. [PDF]
PLoS ONE, 2017 Ecdysteroids are steroid hormones that induce molting and determine developmental timing in arthropods. In insect larva, the prothoracic gland (PG) is a major organ for ecdysone synthesis and release.
Takayoshi Nakaoka +8 more
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Effects of methoxyfenozide on ecdysone receptor complex expression in larval Asian gypsy moth
Open Life Sciences, 2015 As a target of insect growth regulators, the ecdysone receptor complex binds ecdysone agonists to regulate gene transcription, development, and growth.
Wu Shao-ping +6 more
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Interactions of ultraspiracle with ecdysone receptor in the transduction of ecdysone‐ and juvenile hormone‐signaling [PDF]
The FEBS Journal, 2005 Analyses of integration of two‐hormone signaling through the vertebrate nuclear hormone receptors, for which the retinoid X receptor is one partner, have generated a number of mechanistic models, including those described as ‘subordination’ models wherein ligand‐activation of one partner is subordinate to the liganded state of the other partner ...
Fang, Fang +3 more
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The steroid hormone ecdysone regulates growth rate in response to oxygen availability
Scientific Reports, 2022 In almost all animals, physiologically low oxygen (hypoxia) during development slows growth and reduces adult body size. The developmental mechanisms that determine growth under hypoxic conditions are, however, poorly understood.
George P. Kapali +4 more
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