Results 161 to 170 of about 46,368 (260)

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Juvenile hormone signaling is indispensable for late embryogenesis in ametabolous and hemimetabolous insects. [PDF]

BMC Biol
Lv YN, Zeng M, Yan ZY, Zhang PY, Ban N, Yuan DW, Li S, Luan YX, Bai Y.   +8 more
europepmc   +1 more source

The WHO Classification of Genetic Tumour Syndromes: Considerations for Genetics

Clinical Genetics, EarlyView.
The WHO Classification of Tumours underpins the diagnosis of neoplastic conditions. The new WHO classification of genetic tumour syndromes (GTS) provides international standards for their diagnosis. This diagram highlights the chromosomal distribution of the genes involved in the GTS covered in this classification.
Ian A. Cree, Mark J. Arends, Joseph D. Khoury, Erika R. E. Denton, Anthony J. Gill, Alexander J. Lazar, Ian M. Frayling, Stefan M. Pfister, Mark A. Rubin, Katia R. M. Leite, Raymond Dalgleish, Elspeth A. Bruford, Sharon E. Plon, Ada Hamosh, Michael Francis Walsh, Gabrielle Goldman‐Lévy, Harshima Wijesinghe, William D. Foulkes, Dilani Lokuhetty   +18 more
wiley   +1 more source

Receptor tyrosine kinases CAD96CA and FGFR1 function as the cell membrane receptors of insect juvenile hormone. [PDF]

Elife
Li YX, Kang XL, Li YL, Wang XP, Yan Q, Wang JX, Zhao XF.   +6 more
europepmc   +1 more source

Water pollution from swine factory farms poses a threat to endangered and threatened species

Conservation Science and Practice, EarlyView.
Abstract Factory farms, or concentrated animal feeding operations (CAFOs), generate millions of tons of manure each year in the United States. The storage, handling, and land application of this manure leads to air, water, and climate pollution, which disproportionately impacts low‐income communities of color and poses additional public health and ...
Mustafa Saifuddin, Sarah Brickman, Claire S. Huang, Harrison Watson   +3 more
wiley   +1 more source

Histone deacetylases synergistically regulate juvenile hormone signaling in the yellow fever mosquito, Aedes aegypti. [PDF]

Insect Biochem Mol Biol
Gaddelapati SC, Palli SR.
europepmc   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Gold and Clarke Questionnaires Identify Different People With Insulin‐Treated Diabetes and Impaired Awareness of Hypoglycaemia in Almost 60% of Cases: A Post Hoc Analysis From the Hypo‐METRICS Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Gold and Clarke questionnaires are used to identify impaired awareness of hypoglycaemia (IAH) and severe hypoglycaemic event (SHE) risk in people with diabetes (pwD). We explored their overlap, including Clarke's Hypoglycaemia Awareness Status (Clarke‐HAS) subfactor, and subsection differences in SHE incidence (Gold, Clarke, overlap ...
Vaios Koutroukas, Jonah Thomas, Gilberte Martine‐Edith, Aikaterina Tziannou, Patrick Divilly, Uffe Søholm, Claire L. Meek, Simon Heller, Julia K. Mader, Ulrik Pedersen‐Bjergaard, Bastiaan E. de Galan, Eric Renard, Mark L. Evans, Rory J. McCrimmon, Jane Speight, Frans Pouwer, Stephanie A. Amiel, Pratik Choudhary, on behalf of the Hypo‐RESOLVE consortium   +18 more
wiley   +1 more source

Gut symbiotic bacteria enhance reproduction in Spodoptera frugiperda (J.E. Smith) by regulating juvenile hormone III and 20-hydroxyecdysone pathways. [PDF]

Microbiome
Chu B, Ge S, He W, Sun X, Ma J, Yang X, Lv C, Xu P, Zhao X, Wu K.   +9 more
europepmc   +1 more source

Impact of Environmental Conditions on the Spawning Migration of Sea Trout (Salmo trutta L.) in Two Large, Sub‐Arctic River Systems

Fisheries Management and Ecology, EarlyView.
ABSTRACT The global decline in salmonid stocks has increased the need for knowledge of local adaptations and life history strategies of salmonids. In this study, we used radio‐telemetry tracking data from sea trout populations in two large high‐latitude rivers to model upstream spawning migration speed of trout in response to prevailing environmental ...
L. Lähteenmäki, A. Romakkaniemi, R. Huusko, G. Hellström, P. Orell, J. Erkinaro, A. H. Rikardsen, J. Jensen, M. Snickars   +8 more
wiley   +1 more source