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MRI findings in juvenile Huntington's disease [PDF]
Radiology Case Reports, 2021 Juvenile Huntington's disease is a rare neurodegenerative disorder that first affects the basal ganglia. Presented here is a case of juvenile Huntington's disease in an 8-year-old male. Clinical features included epilepsy and developmental delay. Imaging
Patrick Arraj, BS +4 more
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Case report: Cerebellar sparing in juvenile Huntington's disease [PDF]
Frontiers in Neurology, 2023 Juvenile Huntington's disease is an early-onset variant of Huntington's disease, generally associated with large CAG repeats and distinct clinical symptoms. The role of the cerebellum in Huntington's disease has been reevaluated, based on the presence of
Bruno Lopes Santos-Lobato +3 more
doaj +2 more sources
Juvenile Huntington’s disease masquerading as progressive myoclonus epilepsy [PDF]
Epilepsy & Behavior Reports, 2021 Juvenile Huntington’s disease (JHD) has an onset before 20 years of age, and is characterized by behavioural issues, epilepsy, rigidity, bradykinesia and dystonia. It contributes to 0.5–5% of all Huntington disease (HD) cases.
Bina Thakor +2 more
doaj +2 more sources
Juvenile Huntington’s disease: two case reports and a review of the literature [PDF]
Journal of Medical Case Reports, 2020 Background Huntington’s disease is a rare, autosomal dominant neurodegenerative disease characterized by motor, cognitive, and psychiatric symptoms. Usually, the disease symptoms first appear around the age of 40, but in 5–10% of cases, they manifest ...
Sigita Lesinskienė +5 more
doaj +2 more sources
Managing Juvenile Huntington’s Disease [PDF]
Neurodegenerative Disease Management, 2013 Huntington's disease (HD) is a well-recognized progressive neurodegenerative disorder that follows an autosomal dominant pattern of inheritance. Onset is insidious and can occur at almost any age, but most commonly the diagnosis is made between the ages of 35 and 55 years. Onset ≤20 years of age is classified as juvenile HD (JHD).
Oliver W J, Quarrell +5 more
openaire +3 more sources
Special Issue: Juvenile Onset Huntington’s Disease [PDF]
Brain Sciences, 2020 [...]
Peg C. Nopoulos
doaj +3 more sources
Behavioral Deficits in Juvenile Onset Huntington’s Disease [PDF]
Brain Sciences, 2020 Reports of behavioral disturbance in Juvenile-Onset Huntington’s Disease (JOHD) have been based primarily on qualitative caregiver reports or retrospective medical record reviews.
Kathleen E. Langbehn +7 more
doaj +3 more sources
Autonomic Changes in Juvenile-Onset Huntington’s Disease [PDF]
Brain Sciences, 2020 Patients with adult-onset Huntington’s Disease (AOHD) have been found to have dysfunction of the autonomic nervous system that is thought to be secondary to neurodegeneration causing dysfunction of the brain–heart axis. However, this relationship has not
Jordan L. Schultz, Peg C. Nopoulos
doaj +3 more sources
Анналы клинической и экспериментальной неврологии, 2017 Juvenile Huntingtons disease (JHD) manifests in 1st2nddecades of life and accounts for 29% of all cases ofHuntingtons disease; its pathogenic mechanisms are related togenetic anticipation and imprinting.
G. E. Rudenskaya +5 more
doaj +2 more sources
Stem Cell Research, 2023 Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by a mutation in the HTT gene. To generate human-induced pluripotent stem cells (hiPSCs), we used dermal fibroblasts from 1 healthy adult control (K-Pic2), 1 HD manifest ...
Marta Piechota +8 more
doaj +1 more source